Mariana Coutinho Sardo

Assistant Researcher

Contact

Department

  • Chemistry
  • 15.3.20

Research

Links

Latest News

Short CV

Since 2019: Assistant Researcher at CICECO - Aveiro Institute of Materials

2016 - 2018: post-doctoral fellow at CICECO - Aveiro Institute of Materials under the supervision of Doctor Luis Mafra and Professor João Rocha;

2010 - 2016: post-doctoral fellow at CICECO - Aveiro Institute of Materials and Laboratorium für Physikalische Chemie, ETH Zürich supervised by Doctor Luis Mafra, Professor João Rocha and Professor Beat H. Meier; 

2009: PhD in Physical Chemistry: " Weak intermolecular interactions in advanced functional materials: spectroscopic and computational studies” (supervision of Prof. Paulo Ribeiro-Claro), Chemistry Department, University of Aveiro. During this period, 5 months were spent in the University of Malaga, Spain, working in the group of Professor Juan Carlos Otero, developing SERS studies on pharmaceutical compounds;

2005: Degree in Physics and Chemistry (for teaching), Univ. Aveiro (17/20) 

SCIENTIFIC INTERESTS 

- Combining high-resolution solid-state NMR methods, X-ray diffraction and computational approaches to study crystal packing interactions in small molecules (namely pharmaceuticals) and materials - NMR crystallography; 

- Study drug-drug and drug-host interactions of molecular scaffolds as drug delivery systems. 

- NMR characterization of modified nanoporous solid sorbents with potential for gas capture (by using 13C-labelled CO2 in a gas mixture); 

- NMR characterization of porous materials relevant in heterogeneous catalysis (study of Lewis and Brønsted acidity);

OTHER INTERESTS 

- Responsible for preparing and delivering solid-state NMR Hands-on courses (II Jornadas Nacionais de Caracterização de Materiais - 2017 and IV Ibero-American NMR Meeting - 2012). - Co-President of the Young Chemists Group (GQJ) of the Portuguese Chemical Society (SPQ) between 2010-2012 - Member of the organizing committee of several scientific events: Chemistry Olympics competitions, the Portuguese Physics students meeting (2004), International conference on solubility phenomena (2004), Young Portuguese Chemists meeting (2010), European Young Chemists Network (EYCN) delegates assembly (2012) and EYCN contribution to the 4EuCheMS (2012), IV Ibero-American NMR Meeting (2012), SMARTER8 (2024) and PANACEA events (2024; 2025).

Present Research Group

Dr. Luis Mafra; Dr. Ildefonso Marin; Dra. Mirtha Lourenço, Professor João Rocha, Dra. Paula Soares Santos; Daniel Pereira, Márcio Soares, Tiago Morais, Pedro Ouro, Ana Poças, Guilherme Rosa, Andrea Chacón, Renato Vala

Main present collaborators

Dr. Ricardo Vieira (UCoimbra), Dra. Anne Lesage (CNRS-Lyon), Dra. Marina Ilkaeva and Dr. Igor Krivtsov (U. Oviedo), Prof. Manuel Souto (CIQUS), Dr. Manuel Coimbra and Dra. Elisabete Coelho (UA), Dr. Frederick Mentink-Vigier (MagLab), Dra. Laura Salonen (U. Vigo), Dr. Armando Maestro (IKERBASQUE, CSIC, UPV/EHU), Prof. Snorri Sigurdsson (U. Iceland), Prof. Inês Martins (U. Copenhagen), Prof. Mariya Shamzhy (Charles Univ.), Prof. André Martins (U. Tuebingen)

Selected Publications

1. "Comparison of different silica microporous structures as drug delivery systems for in vitro models of solid tumors", Natália Vilaça, Ana F. Machado, Filipa Morais-Santos, Ricardo Amorim, A. Patrícia Neto, Enora Logodin, Manuel F. R. Pereira, Mariana Sardo, João Rocha, Pier Parpot, António M. Fonseca, Fátima Baltazar and Isabel C. Neves, RSC Adv., 2017, 7, 13104-13111.

2. "PAIN with and without PAR: Variants for third-spin assisted heteronuclear polarization transfer", Vipin Agarwal*, Mariana Sardo*, Ingo Scholz, Anja Böckmann, Matthias Ernst and Beat H. Meier, J. Biomol. NMR 2013, 56(4), 365-377. (*authors equally contributed for this work)

 3. "Combining multinuclear high-resolution solid-state MAS NMR and computational methods for resonance assignment of glutathione tripeptide", Mariana Sardo, Renée Siegel, Sérgio M. Santos, João Rocha, José R. B. Gomes, Luis Mafra, J. Phys. Chem. A 2012, 116 (25), 6711–6719.

4. "3D–2D–0D Stepwise Deconstruction of a Water Framework Templated by a Nanoporous Organic–Inorganic Hybrid Host", João Rocha, Fa-Nian Shi, Filipe A. Almeida Paz, Luis Mafra, Mariana Sardo, Luis Cunha-Silva, James Chisholm, Paulo Ribeiro-Claro and Tito Trindade, Chem. Eur. J. 2010, 16, 7741-7749.

Ongoing Supervisions

Ana Teresa Abreu Poças

PhD Student

Andrea Chacón Calderón

PhD Student

Daniel António Cunha Pereira

PhD Student

Márcio Miguel da Silva Soares

PhD Student

Pedro Ouro

PhD Student

Projects

A Pan-European Solid-State NMR Infrastructure for Chemistry-Enabling Access (PANACEA)

Local CoordinatorEuropean Comission
The chemicals industry is one of Europe’s largest manufacturing sectors. Its modernisation relies on the capacity for atomic-level investigation of increasingly complex solid substrates in multifaceted research areas. Advances have been made in the development and use of solid-state nuclear magnetic resonance (NMR) spectroscopy, a powe...

Compreender os mecanismos de sorção em silicatos de Li e Na usados como sorventes de captura de CO2 nos processos de pré/pós- combustão : estratégias para síntese e RMN do estado sólido. (DRI/INDIA/0518/2020)

PartnerFundação para a Ciência e a Tecnologia
Captura de CO2; Silicatos de lítio; Propriedades sorventes; RMN do estado sólido

Delivery vehicles of therapeutic gasotransmitters NO and H2S based on nanoporous materials (PTDC/MED-QUI/28721/2017)

PartnerFundação para a Ciência e a Tecnologia

Especies de CO2 formadas a superficie de materiais porosos para aplicacoes ambientais caracterizadas por RMN de polarizacao nuclear dinamica (GAS2MAT-DNPSENS)

PartnerFundação para a Ciência e a Tecnologia

Polymorphism in pharmaceuticals: new insights from NMR Crystallography (EXPL/QEQ-QFI/2078/2013)

CoordinatorFundação para a Ciência e a Tecnologia
Solid-state NMR spectroscopy Polymorphism in active pharmaceutical ingredients NMR Crystallography Dynamic nuclear polarization

Supported Covalent Organic Frameworks for the Monitoring of Pharmaceutical Pollutants (Charm)

PartnerFundação para a Ciência e a Tecnologia

Unveiling CO2 chemisorption mechanisms in solid adsorbents via surface-enhanced ex(in)-situ NMR (NMR4CO2)

PartnerEuropean Comission
Reaching a record high of 32.5 gigatonnes in 2017, global CO2 emissions from fossil fuel combustion continue to increase. Adsorption is considered a viable technology to reduce CO2 emissions. Because of its lower regeneration cost, amine-modified porous silica (AMPS) is the most promising CO2-adsorbent material for replacing the decades-old liqu...

Publications

Enhancing CO2 Capture Via Fast Microwave-Assisted Synthesis of the CALF-20 Metal–Organic Framework

Daniel Pereira, Mariana Sardo, Ricardo Vieira, Ildefonso Marín-Montesinos, Luís Mafra*
2025, Inorganic Chemistry, 67, 7.

Crystallinity-Enhanced CO2 Adsorption by Sodium Poly(Heptazine Imide) Frameworks

Pedro Ouro, Álvaro Cuevas, Johannes Liessem, Dariusz Mitoraj, Radim Beranek, Eva Díaz, Salvador Ordóñez, Ildefonso Marin-Montesinos, Daniel Pereira, Mariana Sardo, Igor Krivtsov, Luís Mafra, and Marina Ilkaeva
2025, ChemSusChem.

Structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes

Andreas Santamaria, Daniel Pereira, Nisha Pawar, Bernard T. Kelly, Javier Carrascosa-Tejedor, Mariana Sardo, Luís Mafra, Giovanna Fragneto, David J. Owen*, Ildefonso Marín-Montesinos*, Eduardo Guzmán, Nathan R. Zaccai* and Armando Maestro*
2025, Communications Chemistry, 8.

Covalent connectivity of glycogen in brewer's spent yeast cell walls revealed by enzymatic approaches and dynamic nuclear polarization NMR

Bastos, R; Marín-Montesinos, I; Ferreira, SS; Mentink-Vigier, F; Sardo, M; Mafra, L; Coimbra, MA; Coelho, E
2024, CARBOHYDRATE POLYMERS, 324.
ISBN: 1879-1344

Unravelling the structure of CO2 in silica adsorbents: an NMR and computational perspective

Sardo, M; Morais, T; Soares, M; Vieira, R; Ilkaeva, M; Lourenço, MAO; Marín-Montesinos, I; Mafra, L
2024, CHEMICAL COMMUNICATIONS, 60, 30, 4015-4035.
ISBN: 1364-548X

Valorization of Crab Shells as Potential Sorbent Materials for CO2 Capture

Pereira, D; Ilkaeva, M; Vicente, F; Vieira, R; Sardo, M; Lourenço, MAO; Silvestre, A; Marin-Montesinos, I; Mafra, L
2024, ACS OMEGA, 9, 16, 17956-17965.

Detection of helical water flows in sub-nanometer channels

Zelenovskii, P; Soares, M; Bornes, C; Marin-Montesinos, I; Sardo, M; Kopyl, S; Kholkin, A; Mafra, L; Figueiredo, F
2024, NATURE COMMUNICATIONS, 15, 1.
ISBN: 2041-1723

C-P Bond Cleavage Through Hydrogenation in Ruthenium Complexes Supported by P,N Ligands

Cacho, VRG; Veiros, LF; Gomes, CSB; Sardo, M; Figueira, CA; Martins, AM; Ferreira, MJ
2024, INORGANIC CHEMISTRY, 63, 49, 23421-23430.
ISBN: 1520-510X

Engineering phosphatidylinositol-4,5-bisphosphate model membranes enriched in endocytic cargo: A neutron reflectometry, AFM and QCM-D structural study

Pereiraa, D; Santamaria, A; Pawar, N; Carrascosa-Tejedor, J; Sardo, M; Mafra, L; Guzmán, E; Owen, DJ; Zaccai, NR; Maestro, A; Marín-Montesinos, I
2023, COLLOIDS AND SURFACES B-BIOINTERFACES, 227.

One-Shot Resin 3D-Printed Stators for Low-Cost Fabrication of Magic-Angle Spinning NMR Probeheads

Pereira, D; Sardo, M; Marín-Montesinos, I; Mafra, L
2023, ANALYTICAL CHEMISTRY, 95, 27, 10384-10389.

Characterisation of pharmaceutical solids combining NMR, X-ray diffraction and computer modelling

In María Angeles Canales (Eds.), Biophysical Techniques in Drug Discovery
Mariana Sardo, Inês Martins, Chiara Vladiskovic, M.Teresa Duarte, João Rocha, Norberto Masciocchi and Luís Mafra
2018, 120-169, Royal Society of Chemistry.
ISBN: 978-1-78262-733-3

Calculation of NMR tensors: application to small molecule pharmaceutics

In Yuriy A. Abramov (Eds.), Computational Approaches in Pharmaceutical Solid State Chemistry
Luis Mafra, Sérgio Santos, Mariana Sardo, Heather Schmidt
2016, 287-329, John Wiley & Sons, Inc..
ISBN: 9781118700686

Solid-state NMR applications in the structural elucidation of small molecules

In Cid, M-M and Bravo, J. (Eds.), Structure Elucidation in Organic Chemistry: The Search for the Right Tools
Sardo, M., Rocha, J. and Mafra, L.
2015, Wiley-VCH.
ISBN: 978-3-527-33336-3

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".


Privacy and Cookie Policy

Personal data

CICECO-Aveiro Institute of Materials respects your privacy, ensuring confidentiality of personal data you share with the institution through this way, not collecting any personal information about you without your consent, under the terms required by General Data Protection Regulations (RGPD).

The data collected in forms are intended exclusively for processing user requests and will not be used for any other purpose, always safeguarding their confidentiality, under the terms of the protection conferred by the aforementioned regulation.

The collection and processing of data is the responsibility of CICECO and its storage is properly protected, only authorized CICECO employees can access the information within the scope of their functions, always being clear in the respective collection forms the purposes for which they are intended. The remaining issues to be considered in this matter will be handled by the University of Aveiro in accordance with the regime established by the GDPR.

Cookies policy

Cookies are small files with alphanumeric information that are stored on your computer's hard drive by your browser and are intended to improve the user experience and enhance website navigation.

Collection and use of technical information

The cookies used on CICECO are anonymous, and no information about our users that allows their personal identification is stored in them.

The technical information recorded consists of:

  • iP (Internet Protocol) address of the visitor;
  • the type of internet browser used by the website visitor and the respective operating system used;
  • the date and time of the consultation;
  • the pages visited on the site and the documents downloaded
  • The technical information collected is used for statistical purposes only.

Cookies used

Session cookies

These cookies are used to record user preferences, such as the language in which websites are displayed or to maintain authenticated user sessions, and are automatically deleted when the browser is closed.

Persistent cookies

These cookies store information that is needed between sessions. For example, a persistent cookie is set to record that you have been made aware of the cookie policy so that the message regarding this policy is not shown again the next time you visit the website. This cookie remains on the computer until it reaches its expiry date or is deleted by the user.

Data protection

The present privacy policy covers the Information System of the University of Aveiro (SIUA), governed by the General Data Protection Regulations (RGPD) Regulation (EU) No. 2016/679, of April 27th, 2016.

Data Protection Officer

The University of Aveiro has a Data Protection Officer (DPO), who ensures compliance of the processing of personal data with the legislation in force, and is available through the following email address epd@ua.pt.

Close