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PhD Student Fellow, 2019-present, SFRH/BD/144303/2019
This PhD plan includes in silico systematic exploration of the polymer-drug conjugates that can be enzymatically obtained, assessment of drug release profiles and protein reengineering that will be later experimentally assayed, chemically characterized and tested in vitro.
Rational design of a thermostable esterase for the production of high-value bioplastics for biomedical applications
Research Fellow, 2018-2019, MIT-EXPL/ISF/0021/2017
This project is focused on the design of customized thermostable enzyme to produce high-value biopolymers for biomedical applications.
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Introduction of a Glycine Linker Connecting the Heavy and Light Chains in Synthetic Cardosin B-Derived Rennet Changes the Specificity of Subpocket S3′Pedro R. Figueiredo, Sónia F.G. Santos, Beatriz C. Almeida, Isaura Simões and Alexandra T. P. Carvalho
2021, The Journal of Physical Chemistry B,
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Transcription factor allosteric regulation through substrate coordination to zincBeatriz C. Almeida, Jennifer Kaczmarek, Pedro R. Figueiredo, Kristala L. Jones Prather and Alexandra T.P. Carvalho
2021, NAR Genomics and Bioinformatics,
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Human Carboxylesterase 2 in Cocaine MetabolismPedro R.Figueiredo, Ricardo D.González, Alexandra T.P.Carvalho
2021, Molecular Catalysis, 515,
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Enzymatic Synthesis of Poly(caprolactone): A QM/MM StudyPedro R. Figueiredo, Beatriz C. Almeida, Daniel F. A. R. Dourado, Andreia F. Sousa, Armando J. D. Silvestre and Alexandra T. P. Carvalho
2020, ChemCatChem, 12, 19, 4845-4852.
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Polycaprolactone Enzymatic Hydrolysis: A Mechanistic StudyBeatriz C. Almeida, Pedro Figueiredo and Alexandra T. P. Carvalho
2019, ACS Omega, 4, 4,
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Enzymatic Polymerization of PCL-PEG co-polymers for Biomedical ApplicationsPedro Figueiredo, Beatriz C. Almeida and Alexandra T. P. Carvalho
2019, Frontiers in Molecular Biosciences, 6,
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Adenine Derivatives: Promising Candidates for Breast Cancer TreatmentPedro Figueiredo, Marta Costa, Olívia Pontes, Fátima Baltazar and Fernanda Proença
2018, European Journal Of Organic Chemistry,
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From common plastics to sustainable alternatives: A mechanistic study of a green catalystBeatriz C. Almeida; Figueiredo, Pedro; Alexandra T. P. Carvalho
2019,
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Enzymatic transesterification of PCL-PEG co-polymersFigueiredo, Pedro; Beatriz C. Almeida; Alexandra T. P. Carvalho
2019,
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Rational design of enzymatic production of high-value biodegradable polymersAlmeida, Beatriz C.; Pedro Figueiredo; Alexandra T. P. Carvalho
2019,
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Enzymatic synthesis of poly(e-caprolactone): a QM/MM MD studyFigueiredo, Pedro; Almeida, Beatriz C.; Carvalho, Alexandra T. P.
2019,
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Rational design of enzymatic production of high-value biodegradable polymers for biomedical applicationsAlexandra T. P. Carvalho; Pedro R. Figueiredo; Almeida, Beatriz C.
2019,
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Synthesis of poly(e-caprolactone): a bio-based polymer for biomedical applicationsFigueiredo, Pedro; Almeida, Beatriz C.; Carvalho, Alexandra T. P.
2019,
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Rational design of enzymatic production of high value biodegradable polymers for biomedical applicationsAlmeida, Beatriz C.; Figueiredo, Pedro; Alexandra T. P. Carvalho
2019,
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Catalytic cycle of CALB towards the synthesis of poly(e-caprolactone)Figueiredo, Pedro; Carvalho, Alexandra
2019,
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Rational design of enzymes for biopolymer synthesisAlexandra T. P. Carvalho; Pedro R. Figueiredo; Almeida, Beatriz C.
2019,
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Rational design of esterases for biopolymer synthesisPedro R. Figueiredo, Beatriz C. Almeida, Alexandra T. P. Carvalho
2019,
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Synthesis and characterization of new perylenediimides functionalized with dehydroamino acidFigueiredo, Pedro; Proença, Maria Fernanda; Martins, José Alberto
2016,
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Síntese de perilenobisimidas modificadas com derivados de antraquinona e ferroceno (para posterior aplicação como sensores electroquímicos)Figueiredo, Pedro; Proença, Maria Fernanda
2016,
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