Maria Clara Gomes

Assistant Researcher

Ongoing Supervisions

Projects

Development of a multifunctional biomaterial patch for buccal delivery of peptide-analogue treatments (BUCCAL-PEP)

PartnerEuropean Comission
Oral delivery of peptide macromolecules represents significant challenges for pharmaceutical research, including low bioavailability, dosage control and undesirable food interactions. The intention of the EU-funded BUCCAL-PEP project is to develop a technological platform for oromucosal delivery suitable for a broad range of peptide-ana...

High-tech sustainable biofabrication for advancing personalized healthcare (LEGO)

PartnerFundação para a Ciência e a Tecnologia
This research proposal aims to engineer and validate, for the first time, a simple, sustainable, and highly translational methodology for obtaining extracellular matrix-rich tissue-specific bioinks. Patient's own cells will be the main building blocks for the development of realistic microtissues, which will be used to engineer a h...

Metastasis Exploration in the Bone Microenvironment - Breast Cancer Edition (METABONE)

CoordinatorFundação para a Ciência e a Tecnologia
METABONE is a collaborative research project that is all about creating a 3D model in a lab to explore how breast cancer spreads to the bones. To do this, we are using robots to automate tiny tasks and clever liquid capsules that act like mini-labs. The goal is to get an accurate picture of the complex bone environment. This platform is...

PRInted Symbiotic Materials as a dynamic platform for Living Tissues production (PRISM-LT)

PartnerEuropean Comission
The EU-funded PRISM-LT project will use a hybrid living materials concept to create a flexible platform for living tissue manufacturing. The innovative bio-ink will contain stem cells integrated into a supporting matrix with engineered helper bacteria or yeast cells. The bioprinting process will produce a 3D patterned structure where stem cells ...

Publications

Supramolecular assembly of multi-purpose tissue engineering platforms from human extracellular matrix

Ladeira, B; Gomes, M; Wei, KC; Custódio, C; Mono, J
2025, BIOMATERIALS, 320.

Pierceable, Storable, and Manipulable Liquid Capsules for Precise Monitoring and Efficient Cargo Transport in Biotechnological Advances

Pinho, AR; Wang, CM; Gomes, MC; Mano, JF
2025, ADVANCED FUNCTIONAL MATERIALS, 35, 25.

Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies

Martins, EAG; Deus, IA; Gomes, MC; Silva, AS; Mano, JF; Custódio, CA
2025, ADVANCED HEALTHCARE MATERIALS, 14, 1.

The Future of Automated Tissue Engineering: Robotic-Assisted Strategies for Complex 3D Tissue Bottom-Up Assembly

Almeida, AM; Mazeda, J; Pinho, AR; Gomes, MC; Mano, JF
2025, ADVANCED MATERIALS TECHNOLOGIES, 10, 16.

Synergistic effect of proteins and tannic acid-yielding systems with improved mechanical performance for use in load-bearing tissues

Gomes, MC; Mortier, C; Haugen, HJ; Blaker, JJ; Mano, JF
2025, MATERIALS RESEARCH EXPRESS, 12, 7.

Bioactive Self-Regulated Liquified Microcompartments to Bioengineer Bone-Like Microtissues

Pinho, AR; Gomes, MC; Costa, DCS; Mano, JF
2024, SMALL, 20, 9.
ISBN: 1613-6829

Human Platelet Lysate-Derived Nanofibrils as Building Blocks to Produce Free-Standing Membranes for Cell Self-Aggregation

Monteiro, C; Gomes, MC; Bharmoria, P; Freire, MG; Coutinho, JAP; Custódio, CA; Mano, JF
2024, ACS NANO, 18, 24, 15815-15830.
ISBN: 1936-086X

Designing of a Multifunctional 3D-Printed Biomimetic Theragenerative Aerogel Scaffold via Mussel-Inspired Chemistry: Bioactive Glass Nanofiber-Incorporated Self-Assembled Silk Fibroin with Antibacterial, Antiosteosarcoma, and Osteoinductive Properties

Abie, N; Ünlü, C; Pinho, AR; Gomes, MC; Remmler, T; Herb, M; Grumme, D; Tabesh, E; Shahbazi, MA; Mathur, S; Mano, JF; Maleki, H
2024, ACS APPLIED MATERIALS & INTERFACES, 16, 18, 22809-22827.
ISBN: 1944-8252

A Self-Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture

Zargarzadeh, M; Gomes, MC; Patrício, SG; Custódio, CA; Mano, JF
2023, ADVANCED FUNCTIONAL MATERIALS, 33, 48.

Self-Assembly of Platelet Lysates Proteins into Microparticles by Unnatural Disulfide Bonds for Bottom-Up Tissue Engineering

Gomes, MC; Pinho, AR; Custódio, C; Mano, JF
2023, ADVANCED MATERIALS, 35, 41.

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