Joana Teixeira Albuquerque Gomes Marques

Scientific Interests

1. Synthesis of novel ruthenium complexes for osteosarcoma chemotherapy 
2. Cyclodextrins as nano-sized molecular capsules for biomimetic Ru(II) antitumorals 
3. In-vitro cytotoxic profile of novel ruthenium complexes in human cell lines

Present Research Group

Doctor Susana S. Braga - CICECO, University of Aveiro

Doctor Maria Paula Marques - QFM, FCTUC, University of Coimbra 

Selected Publications

Structural Studies and Cytotoxicity of Trimethyl(ferrocenylmethyl)ammonium Iodide Encapsulated in β-Cyclodextrin 
Sofia M. Bruno, José A. Fernandes, Joana Marques, Sara C. Neto, Paulo Jorge Ribeiro-Claro, Martyn Pillinger, Filipe A. Almeida Paz, Maria Paula M. Marques, Susana S. Braga, Isabel S. Gonçalves, Eur. J. Inorg. Chem. (2011). doi: 10.1002/ejic.20110065 Arcyriaflavin A monohydrate 
José A. Fernandes, Filipe A. Almeida Paz, Joana Marques, Maria Paula M. Marques, Susana S. Braga, Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 67 (2011) o57-o59.  Nuclear Magnetic Resonance (NMR) Study of the Effect of Cisplatin on the Metabolic Profile of MG-63 Osteosarcoma Cells 
Iola F. Duarte, Inês Lamego, Joana Marques, Maria Paula M. Marques, Benjamin J. Blaise, Ana M. Gil, J. Proteome Res. 9 (2010) 5877-5886.  A glycine ruthenium trithiacyclononane complex and its molecular encapsulation using cyclodextrins 
Joana Marques, Teresa M. Santos, Maria Paula M. Marques, Susana S. Braga, Dalton Trans. (2009) 9812-9819.  Analytical Approaches toward Successful Human Cell Metabolome Studies by NMR Spectroscopy 
Iola F. Duarte, Joana Marques, Ana F. Ladeirinha, Cládia Rocha, Inês Lamego, Rita Calheiros, Tânia M. Silva, Maria P. M. Marques, Joana B. Melo, Isabel M. Carreira, Ana M. Gil, Anal. Chem. 81 (2009) 5023-5032.  Cyclodextrins improve the Antimicrobial Activity of the chloride salt of Ruthenium(II) Chloro-phenanthroline-trithiacyclononane 
Joana Marques, Teresa M. Braga, Filipe A. Almeida Paz, Teresa M. Santos, Maria de Fátima Silva Lopes, Susana S. Braga, Biometals 22 (2009) 541-556.  Structural Studies on Supramolecular Adducts of Cyclodextrins with the Complex [Ru([9]aneS3)(bpy)Cl]Cl 
Joana Marques, Lúcia Anjo, Maria Paula M. Marques, Teresa M. Santos, Filipe A. Almeida Paz, Susana S. Braga, J. Organomet. Chem. 693 (2008) 3021-3028.  Effects of Radiation in Cellular Cultures 
M. Filomena Botelho, A. Cristina Santos, M. Carmo Lopes, Marta Pinto, Isabel Carreira, Inês Aleixo, Inês Rolo, Luís Neves, Ricardo Costa, Rosemeyre Cordeiro, Cláudia Ferreira, Gilberto Almeida, Hugo Tavares, Joana Marques, João Castro, M. João Bártolo, Stud. Appl. Electromagn. Mech. 29 (2008) 67-71.


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