Samuel Jacques André Guieu

Junior Researcher

Short CV

Postdoctoral Fellow............................................................ Mar. 10-present

University of Aveiro, Portugal, with Pr A. M. S. Silva and Pr J. Rocha, FCT fellowship

Postdoctoral Fellow............................................................. Jan. 09-Dec.10

University of British Columbia, Vancouver, Canada,with Pr M. J. MacLachlan, Lavoisier Fellowship

PhD in Organic Chemistry ..................................................... Sept. 05-Dec. 08

École Normale Supérieure, Université Pierre et Marie Curie Paris 6, France

"Synthesis of multidifferentiated cyclodextrins and Platform chirality evidenced through catalysis", with Pr P. Sinaÿ and Pr M. Sollogoub

 Master II in Organic and Bioorganic Chemistry........................... Sept. 04-July 05

École Normale Supérieure, Université Pierre et Marie Curie Paris 6, France

"Toward gem-difluorocarba-mannose synthesis" with Pr P. Sinaÿ and Pr M. Sollogoub

French “Aggregation de Sciences Physiques, Option Chimie” : admittetd 21st... Sept. 03-July 04

Ecole Normale Supérieure de Lyon

Erasmus Student.................................................................. Jan. 03-July 03

Leiden Institut of Chemistry, Gorleaus laboratories, Leiden University, The Netherlands,  “N,O-containing ligands for copper-catalysed oxidation reactions”with Pr J. Reedijk

Master I in Physical Chemistry.................................................. Sept. 01-Jan. 03

Ecole Normale Supérieure de Lyon

“Synthesis and optical studies of new octupolar chromophores for non-linear optic”

with Pr M. Blanchard-Desce in Rennes, France

 

Scientific interests

- Luminescent organic crystals

- Fluorophores for cellular imaging

- Selective modification of cyclodextrins

- Supramolecular chemistry

- Schiff-base macrocycles

Main collaborators

- Pr Artur M. S. Silva (QOPNA, University of Aveiro, Portugal): Organic synthesis.

- Pr João Rocha (CICECO, University of Aveiro, Portugal): Material synthesis.

- Pr Matthieu Sollogoub (Université Pierre et MArie Curie, Paris 6, France): Selective modifications of cyclodextrins

- Pr Mark J. MacLachlan (University of British-Columbia, Canada): Schiff-base macrocycles and metallo-macrocycles.

- Dr Sandra I. Vieira (Neuroscience Laboratory, Center for Cell Biology, Health Sciences Department, University of Aveiro,Portugal): Cellular imaging.

- Pr Paulo J. A. Ribeiro-Claro (CICECO, University of Aveiro, Portugal): Computational spectroscopy.

Selected publications

1) "New N,O-containing ligands for the biomimetic copper-catalyzed polymerization of 2,6-dimethylphenol", S. J. A. Guieu, A. M. M. Lanfredi, C. Massera, L. D. Pachon, P. Gamez and J. Reedijk, Catalysis Today 2004, 96, pp259-264.

2) "Gem-Difluorocarbasugars, the cases of mannose and galactose", J. Sardinha, S. Guieu, A. Deleuze, M. C. Fernández-Alonso, A. P. Rauter, P. Sinaÿ, J. Jiménez-Barbero, M. Sollogoub, Carbohydr. Res. 2007, 342, pp1689-1703.

3) "Multiple homo and hetero-functionalisations of alpha-cyclodextrin through oriented deprotections", S. Guieu, M. Sollogoub, J. Org. Chem. 2008, 73(7), pp2819 -2828.

4) "Photocontrol of Single-Chain DNA Conformation in Cell-Mimicking Micro-Compartments", M. Sollogoub, S. Guieu, M. Geoffroy, A. Yamada, A. Estevez-Torres, K. Yoshikawa, D. Baigl, ChemBioChem. 2008, 9, pp1201-1206.

5) "Regiospecific Tandem Azide-Reduction/Deprotection To Afford Versatile Amino Alcohol-Functionnalized alpha- and béta-Cyclodextrins", S. Guieu, M. Sollogoub, Angew. Chem. Int. Ed. 2008, 47, pp7060-7063.

6) "Can hetero-polysubstituted cyclodextrins be considered as inherently chiral concave molecules?", S. Guieu, E. Zaborova, Y. Blériot, G. Poli, A. Jutand, D. Madec, G. Prestat, M. Sollogoub, Angew. Chem. Int. Ed. 2010, 49, pp2314-2318.Thumbnail image of graphical abstract

7) "Synthesis and Electrochemical Study of an Original Copper(II)-Capped Salen–Cyclodextrin Complex", E. Deunf, E. Zaborova, S. Guieu, Y. Blériot, J.-N. Verpeaux, O. Buriez, M. Sollogoub, C. Amatore, Eur. J. Inorg. Chem. 2010, pp4720–4727.

8) "Columnar Organization of Head-to-Tail Self-Assembled Pt4 Rings", P. D. Frischmann, S. Guieu, R. Tabeshi, M. J. MacLachlan, J. Am. Chem. Soc. 2010, 132, pp7668–7675.

Highlighted as Editor’s Choice in Science 2010, 329,  15.

9) "Cavitand supported tetraphosphine: cyclodextrin offers a useful platform for Suzuki-Miyaura cross-coupling", E. Zaborova, J. Deschamp, S. Guieu, Y. Blériot, G. Poli, M. Ménand, D. Madec, G. Prestat,  M. Sollogoub, Chem. Commun. 2011, 47, pp9206-9208.

Highlighted as Editor’s Choice in ChemInform 2011, 42, Issue 42.

10) "Campestarenes: novel shape-persistent Schiff base macrocycles with 5-fold symmetry", S. Guieu, A. K. Crane, M. J. MacLachlan, Chem. Commun. 2011, 47, pp1169–1171.

11) "Synthesis and characterization of linear and macrocyclic ligands with multiple hemisalen pockets", S. Guieu, Synthetic Communications 2012, 42:21, pp3177-3186.

12) "Sterically-Limited Self-Assembly of Pt4 Macrocycles into Discrete Noncovalent Nanotubes: Porous Supramolecular Tetramers and Hexamers", P. D. Frischmann, B. J. Sahli, S. Guieu, B. O. Patrick, M. J. MacLachlan, Chem. Eur. J. 2012, 18, pp13712-13721.

13) "Dimethyl 5,5'-methylenebis(2-hydroxybenzoate)", S. Guieu, P. Brandão, J. Rocha, A. M. S. Silva, Acta Cryst. 2012. E68, o1404.

14) "Supramolecular organization of bis(3-halo-4-dimethylaminobenzylidene)hydrazines", S. Guieu, J. Rocha, A. M. S. Silva, J. Mol. Struct. 2013, 1035, pp1-5.

15) "Synthesis of Unsymmetrical Methylenebisphenol Derivatives", S. Guieu, J. Rocha, A. M. S. Silva, Synlett 2013, 24, pp762-764.

16) "Synthesis, crystal structure,and luminescence of tetrakis(4-methoxyphenyl)methane", S. Guieu, J. Rocha, A. M. S. Silva, Tetrahedron Letters 2013, 54, pp2870-2873.

17) "Crystallization-induced light-emission enhancement of diphenylmethane derivatives", S. Guieu, J. Rocha, A. M.S. Silva, Tetrahedron 2013, 69, pp9329-9334.

Ongoing Supervisions

Publications

Curcumin-based molecular probes for fluorescence imaging of fungi

Ferreira, JRM; Alves, M; Sousa, B; Vieira, SI; Silva, AMS; Guieu, S; Cunha, A; da Silva, RN
2023, ORGANIC & BIOMOLECULAR CHEMISTRY, 21, 7, 1531-1536.

Locking the GFP Fluorophore to Enhance Its Emission Intensity

Ferreira, JRM; Esteves, CIC; Marques, MMB; Guieu, S
2023, MOLECULES, 28, 1.

Excited-State Proton Transfer in Luminescent Dyes: From Theoretical Insight to Experimental Evidence

Fontes, LFB; Rocha, J; Silva, AMS; Guieu, S
2023, CHEMISTRY-A EUROPEAN JOURNAL, 29, 57.

Three-dimensional nanofibrous and porous scaffolds of poly(ε-caprolactone)-chitosan blends for musculoskeletal tissue engineering

Pereira, AL; Semitela, A; Girao, AF; Completo, A; Marques, PAAP; Guieu, S; Fernandes, MHV
2023, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 111, 7, 950-961.

Smartphone-based Fluorescence System for Protein Aggregates Detection

Sousa, C; Direito, I; Guieu, S; André, P; Helguero, L; Domingues, MF; Alberto, N
2023, 2023 IEEE 7TH PORTUGUESE MEETING ON BIOENGINEERING, ENBENG, 108-111.
ISBN: 979-8-3503-2257-6

Influence of the Intramolecular Hydrogen Bond on the Fluorescence of 2-ortho-Aminophenyl Pyridines

Esteves, CIC; Fontes, LFB; Rocha, J; Silva, AMS; Guieu, S
2022, CHEMISTRY-A EUROPEAN JOURNAL, 28, 53.

Mild Synthesis of Symmetric 3,5-Disubstituted Nitrobenzenes

Francisco, TN; Sousa, JLC; Guieu, S; Silva, AMS; Albuquerque, HMT
2022, SYNLETT, 33, 15, 1505-1510.

Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes

Albuquerque, HMT; da Silva, RN; Pereira, M; Maia, A; Guieu, S; Soares, AR; Santos, CMM; Vieira, SI; Silva, AMS
2022, ACS MEDICINAL CHEMISTRY LETTERS, 13, 3, 443-448.

Straightforward synthesis of thiazolo[5,4-c]isoquinolines from dithiooxamide and 2-halobenzaldehydes

Costa, LD; Guieu, S; Faustino, MDF; Tome, AC
2022, NEW JOURNAL OF CHEMISTRY, 46, 8, 3602-3615.

Benzimidazole-Based N,O Boron Complexes as Deep Blue Solid-State Fluorophores

Vaz, PAAM; Rocha, J; Silva, AMS; Guieu, S
2021, MATERIALS, 14, 15.
ISBN: 1996-1944

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