Solubilities of Amino Acids in Aqueous Solutions of Chloride or Nitrate Salts of Divalent (Mg2+ or Ca2+) Cations

  1. Home
  2. Research
  3. Publications

abstract

The solubilities of glycine, L-leucine, L-phenylalanine, and L-aspartic acid were measured in aqueous MgCl2, Mg(NO3)(2), CaCl2,, and Ca(NO3)(2) solutions with concentrations ranging from 0 to 2 mol/kg at 298.2 K. The isothermal analytical method was used combined with the refractive index measurements for composition analysis guaranteeing good accuracy. All salts induced a salting-in effect with a higher magnitude for those containing the Ca2+ cation. The nitrate anions also showed stronger binding with the amino acids, thus increasing their relative solubility more than the chloride anions. In particular, calcium nitrate induces an increase in the amino acid solubility from 2.4 (glycine) to 4.6 fold (L-aspartic acid) compared to the corresponding value in water. Amino acid solubility data in aqueous MgCl2 and CaCl2 solutions collected from the open literature were combined with that from this work, allowing us to analyze the relations between the amino acid structure and the salting-in magnitude.

keywords

PROTEIN SOLUBILITY; MAGNESIUM-CHLORIDE; TRANSITION; BINDING; GLYCINE; CHARGE; AGENT

subject category

Thermodynamics; Chemistry; Engineering

authors

Aliyeva, M; Brandao, P; Gomes, JRB; Coutinho, JAP; Ferreira, O; Pinho, SP

our authors

foto João Manuel Costa Araújo Pereira Coutinho

João Manuel Costa Araújo Pereira Coutinho

Director
foto José R. B. Gomes

José R. B. Gomes

Principal Researcher
foto Paula Cristina Ferreira da Silva Brandão

Paula Cristina Ferreira da Silva Brandão

Assistant Researcher
no photo

Simão Pedro de Almeida Pinho

Collaborator

Groups

G1 - Porous Materials and Nanosystems
G4 - Renewable Materials and Circular Economy
G6 - Virtual Materials and Artificial Intelligence

Projects

CICECO - Aveiro Institute of Materials (UIDB/50011/2020)

CICECO - Aveiro Institute of Materials (UIDP/50011/2020)

Associated Laboratory CICECO-Aveiro Institute of Materials (LA/P/0006/2020)

acknowledgements

This work was developed within the scope of the project CIMO-Mountain Research Center, UIDB/00690/2020 and LA/P/0007/2020 and CICECO-Aveiro Institute of Materials, UIDB/50011/2020 & UIDP/50011/2020 and LA/P/0006/2020, financed by national funds through the Portuguese Foundation for Science and Technology (FCT)/MCTES. Mehriban Alyieva thanks FCT and European Social Fund (ESF) for her Ph.D. grant (SFRH/BD/139355/2018).

Share this project:

Related Publications

Publication Details

type
Journal Article
year
2022
journal
JOURNAL OF CHEMICAL AND ENGINEERING DATA
volume
67
publisher
AMER CHEMICAL SOC
issn
0021-9568
issue
6
digital object identifier
10.1021/acs.jced.2c00148
web of science article identifier
WOS:000810302200001

Journal Metrics (JCR 2019)

Journal Impact Factor
2.369
Journal Impact Factor (5 yrs)
2.503
category normalized journal percentile
53.135

Citations

Social Interaction

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".


Privacy and Cookie Policy

Personal data

CICECO-Aveiro Institute of Materials respects your privacy, ensuring confidentiality of personal data you share with the institution through this way, not collecting any personal information about you without your consent, under the terms required by General Data Protection Regulations (RGPD).

The data collected in forms are intended exclusively for processing user requests and will not be used for any other purpose, always safeguarding their confidentiality, under the terms of the protection conferred by the aforementioned regulation.

The collection and processing of data is the responsibility of CICECO and its storage is properly protected, only authorized CICECO employees can access the information within the scope of their functions, always being clear in the respective collection forms the purposes for which they are intended. The remaining issues to be considered in this matter will be handled by the University of Aveiro in accordance with the regime established by the GDPR.

Cookies policy

Cookies are small files with alphanumeric information that are stored on your computer's hard drive by your browser and are intended to improve the user experience and enhance website navigation.

Collection and use of technical information

The cookies used on CICECO are anonymous, and no information about our users that allows their personal identification is stored in them.

The technical information recorded consists of:

  • iP (Internet Protocol) address of the visitor;
  • the type of internet browser used by the website visitor and the respective operating system used;
  • the date and time of the consultation;
  • the pages visited on the site and the documents downloaded
  • The technical information collected is used for statistical purposes only.

Cookies used

Session cookies

These cookies are used to record user preferences, such as the language in which websites are displayed or to maintain authenticated user sessions, and are automatically deleted when the browser is closed.

Persistent cookies

These cookies store information that is needed between sessions. For example, a persistent cookie is set to record that you have been made aware of the cookie policy so that the message regarding this policy is not shown again the next time you visit the website. This cookie remains on the computer until it reaches its expiry date or is deleted by the user.

Data protection

The present privacy policy covers the Information System of the University of Aveiro (SIUA), governed by the General Data Protection Regulations (RGPD) Regulation (EU) No. 2016/679, of April 27th, 2016.

Data Protection Officer

The University of Aveiro has a Data Protection Officer (DPO), who ensures compliance of the processing of personal data with the legislation in force, and is available through the following email address epd@ua.pt.

Close