resumo
A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.
palavras-chave
CELLULOSE; HYDROGELS; COMPOSITES; SCAFFOLDS; DIFFUSION; DELIVERY; PHEMA
categoria
Biotechnology & Applied Microbiology; Research & Experimental Medicine
autores
Figueiredo, AGPR; Figueiredo, ARP; Alonso-Varona, A; Fernandes, SCM; Palomares, T; Rubio-Azpeitia, E; Barros-Timmons, A; Silvestre, AJD; Neto, CP; Freire, CSR
nossos autores
Ana Margarida Madeira Viegas de Barros Timmons
Professor associado
Armando Jorge Domingues Silvestre
Professor Catedrático
Carlos Pascoal Neto
Diretor do Raiz
Carmen Sofia da Rocha Freire Barros
Investigador Coordenadoragradecimentos
Andrea G. P. R. Figueiredo and Susana C. M. Fernandes thank the Fundacao para a Ciencia e Tecnologia (Portugal) for their Scientific Research Grants (SFRH/BPD/63219/2009 and SFRH/BPD/70119/2010, resp.), cofinancing by POPH/ESF Program. The authors thank CICECO (Pest-C/CTM/LA0011/2013) and FCT for funding within the scope of the