Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

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abstract

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.

keywords

CELLULOSE; HYDROGELS; COMPOSITES; SCAFFOLDS; DIFFUSION; DELIVERY; PHEMA

subject category

Biotechnology & Applied Microbiology; Research & Experimental Medicine

authors

Figueiredo, AGPR; Figueiredo, ARP; Alonso-Varona, A; Fernandes, SCM; Palomares, T; Rubio-Azpeitia, E; Barros-Timmons, A; Silvestre, AJD; Neto, CP; Freire, CSR

our authors

foto Ana Margarida Madeira Viegas de Barros Timmons

Ana Margarida Madeira Viegas de Barros Timmons

Associate Professor
foto Armando Jorge Domingues Silvestre

Armando Jorge Domingues Silvestre

Full professor
foto Carlos Pascoal Neto

Carlos Pascoal Neto

Raiz Director
foto Carmen Sofia da Rocha Freire Barros

Carmen Sofia da Rocha Freire Barros

Coordinating Researcher

Groups

G1 - Porous Materials and Nanosystems
G4 - Renewable Materials and Circular Economy

Projects

Centre for Research in Ceramics and Composite Materials - CICECO (LA0011: 2013-2014) (PEst-C/CTM/LA0011/2013)

RMNE-UA-National Network of Electron Microscopy (REDE/1509/RME/2005 )

Laboratório de Análises Térmicas (REEQ/515/CTM/2005)

acknowledgements

Andrea G. P. R. Figueiredo and Susana C. M. Fernandes thank the Fundacao para a Ciencia e Tecnologia (Portugal) for their Scientific Research Grants (SFRH/BPD/63219/2009 and SFRH/BPD/70119/2010, resp.), cofinancing by POPH/ESF Program. The authors thank CICECO (Pest-C/CTM/LA0011/2013) and FCT for funding within the scope of the

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Publication Details

type
Journal Article
year
2013
journal
BIOMED RESEARCH INTERNATIONAL
article number
698141
publisher
HINDAWI PUBLISHING CORPORATION
issn
2314-6133
digital object identifier
10.1155/2013/698141
web of science article identifier
WOS:000324414300001

Journal Metrics (JCR 2019)

Journal Impact Factor
2.276
Journal Impact Factor (5 yrs)
2.858
category normalized journal percentile
37.521

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