resumo
Sustainable extraction processes based on alternative solvents to recover bioactive compounds of different raw materials have been highlighted as excellent alternatives to supply the needs of society towards a bioeconomy strategy. Little is known about the safety and biological effect of compounds extracted by these processes. In this work, camtenoids from Bactris gasipaes wastes obtained by an IL-based process were investigated in terms of safety, anti-inflammatory and, antioxidant activity in a high-fat-diet animal model on the kidney. Wistar rats were supplemented or not by camtenoids extracted with IL or VOS. The animals supplemented with carotenoids had lower weight than control and high-fat diets. In the animals supplemented with carotenoids, the group IL improved anti-inflammatory and antioxidant activity compared with carotenoids obtained by VOS. Also, the group HFD-VOS showed moderate-severe injuries on the kidney. Then, ILs could represent a novel tool for natural pigments safely applied to food industry.
palavras-chave
OXIDATIVE STRESS; OBESITY; DISEASE; DIET; FOOD
categoria
Chemistry; Food Science & Technology
autores
Santamarina, AB; Mesquita, LM; Casagrande, BP; Sertorio, MN; de Souza, DV; Mennitti, LV; Ribeiro, DA; Estadella, D; Ventura, SPM; de Rosso, VV; Pisani, LP
nossos autores
Sónia Patrícia Marques Ventura
Professor AuxiliarProjectos
Collaboratory for Emerging Technologies, CoLab (EMERGING TECHNOLOGIES)
agradecimentos
This work was supported by Fundacao de Amparo a` Pesquisa do Estado de Sao Paulo-FAPESP through fellowships (2016/18910; 2016/23242-8, 2020/04448-0, and 2018/10705-5) , and to CNPq - Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, fellowship 305725/2020-3. This work was developed within the scope of the project CICECO-Aveiro Institute of Materials, UIDB/50011/2020 & UIDP/50011/2020, financed by national funds through the Portuguese Foundation for Science and Technology/MCTES.