Frontiers in Biomaterials: Chitosan Based Materials and its Applications
authors Poliana P Lopes, Nathalie B Barroca, Ana Luísa Daniel-da-Silva, Bárbara J Leite Ferreira
editors Guilherme Luiz Dotto, Sergio Paulo Campana-Filho and Luiz Antonio de Almeida Pinto
chapter title Application of Chitosan Based Materials for Drug Delivery
nationality International
abstract One of the main challenges in drug delivery field is the development of formulations or devices designed to allow the transport of a suitable amount of the active pharmaceutical substance to the site of action in the body, and improve its efficacy by controlling the rate, time and place of release. The distribution of the drug to tissues different than the target place is unnecessary, wasteful, and a potential cause of toxicity. Chitosan, a versatile hydrophilic polysaccharide derived from chitin, is a non-toxic, biocompatible and biodegradable polymer which has attracted significant scientific interest, for its fundamental role in the progress of drug delivery technology. This natural biopolymer has inspired the development of safe and effective drug carrier systems due to its unique physicochemical and biological characteristics. The cationic character, exclusive of the chitosan, is …
publisher Bentham Science Publishers
isbn 978-1-68108-486-2
year published 2017
beginning page 181
ending page 248
book digital object identifier (doi) 10.2174/97816810848551170301

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