abstract
A nanocomposite that incorporates cobalt oxide (Co3O4) and nanodiamond (ND) can present both high magnetism (Co3O4) and high hardness (ND). ND particles have potential applications in a variety of fields such as protein immobilization, biosensors, therapeutic molecule delivery and bio-imaging. However, limited information is available in literature on the in-situ synthesis of biocompatible magnetic materials and also on their potential biotoxicity as a result of their entry into environmental compartments and subsequent interaction with biota. In this work, a new kind of bio-compatible magnetic material carboxylated nanodiamond (cND) and Co3O4 was synthesized to obtain the cND-Co3O4 nanocomposite. The synthesis procedure involved in-situ and chemical reduction of cobalt chloride (CoCl2 6H(2)O) and sodium borohydrate (NaBH4). The synthesized cND-Co3O4 nanocomposite was characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and X-ray photoelectron spectroscopy. The cyto-genotoxicity of the synthesized nanocomposite material was studied by using onion (Allium cepa L.) as a test model with concentrations of 5, 10 and 20 mu g/ml. The study was also extended to cND and Co3O4 materials for comparison purpose. Co3O4 and cND exhibited their contrasting effects on mitosis and other cyto-genotoxic indices studied herein. This work provided fundamental data on the synthesis and the bio-toxicity of the cND-Co3O4 nanocomposite, which, in turn, can help to expand their multidisciplinary applications. (C) 2017 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
keywords
CO3O4 NANOPARTICLES; SURFACE FUNCTIONALIZATION; WASTE-WATER; THIN-FILMS; TOXICITY; DEGRADATION; DETONATION; PARTICLES; MOCVD; CELLS
subject category
Materials Science; Metallurgy & Metallurgical Engineering
authors
Sundar, LS; Anjum, NA; Ferro, MC; Pereira, E; Singh, MK; Sousa, ACM
our authors
Marta Ascenção Carmona Ferro
Laboratory OfficerGroups
acknowledgements
The authors acknowledge the financial support from Foundation for the Science and Technology (FCT, Portugal) and, in particular, the funding through the post-doctoral grant SFRH/BPD/100003/2014 (LSS) and the 2013 FCT Investigator programme (MKS). NAA (SFRH/BPD/84671/2012) and EP gratefully acknowledge the partial financial supports received from FCT (Government of Portugal), the Aveiro University Research Institute/CESAM (UID/AMB/50017/2013), and "COMPETE" through Project no. FCOMP-01-0124-FEDER-02800 (FCT PTDC/AGR-PRO/4091/2012).