Latest Advances on Bacterial Cellulose-Based Materials for Wound Healing, Delivery Systems, and Tissue Engineering

abstract

Bacterial cellulose (BC) is a nanocellulose form produced by some nonpathogenic bacteria. BC presents unique physical, chemical, and biological properties that make it a very versatile material and has found application in several fields, namely in food industry, cosmetics, and biomedicine. This review overviews the latest state-of-the-art usage of BC on three important areas of the biomedical field, namely delivery systems, wound dressing and healing materials, and tissue engineering for regenerative medicine. BC will be reviewed as a promising biopolymer for the design and development of innovative materials for the mentioned applications. Overall, BC is shown to be an effective and versatile carrier for delivery systems, a safe and multicustomizable patch or graft for wound dressing and healing applications, and a material that can be further tuned to better adjust for each tissue engineering application, by using different methods.

keywords

MESENCHYMAL STEM-CELLS; IN-VITRO; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS; NANOFIBROUS SCAFFOLD; CONTROLLED-RELEASE; BIOGLASS SCAFFOLD; DRUG-RELEASE; MUSCLE-CELLS; NANOCELLULOSE

subject category

Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology

authors

Carvalho, T; Guedes, G; Sousa, FL; Freire, CSR; Santos, HA

our authors

acknowledgements

T.C. and G.G. contributed equally to this work. T.C. acknowledges Fundacao para a Ciencia e a Tecnologia (FCT), for the Ph.D. grant SFRH/BD/130458/2017. F.L.S. acknowledges FCT for the researcher contract IF/00222/2015. H.A.S. acknowledges financial support from the HiLIFE Research Funds and the Sigrid Juselius Foundation.

Share this project:

Related Publications

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".