abstract
Bacterial cellulose (BC) is a nanocellulose form produced by some nonpathogenic bacteria. BC presents unique physical, chemical, and biological properties that make it a very versatile material and has found application in several fields, namely in food industry, cosmetics, and biomedicine. This review overviews the latest state-of-the-art usage of BC on three important areas of the biomedical field, namely delivery systems, wound dressing and healing materials, and tissue engineering for regenerative medicine. BC will be reviewed as a promising biopolymer for the design and development of innovative materials for the mentioned applications. Overall, BC is shown to be an effective and versatile carrier for delivery systems, a safe and multicustomizable patch or graft for wound dressing and healing applications, and a material that can be further tuned to better adjust for each tissue engineering application, by using different methods.
keywords
MESENCHYMAL STEM-CELLS; IN-VITRO; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS; NANOFIBROUS SCAFFOLD; CONTROLLED-RELEASE; BIOGLASS SCAFFOLD; DRUG-RELEASE; MUSCLE-CELLS; NANOCELLULOSE
subject category
Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology
authors
Carvalho, T; Guedes, G; Sousa, FL; Freire, CSR; Santos, HA
our authors
Groups
G2 - Photonic, Electronic and Magnetic Materials
G4 - Renewable Materials and Circular Economy
acknowledgements
T.C. and G.G. contributed equally to this work. T.C. acknowledges Fundacao para a Ciencia e a Tecnologia (FCT), for the Ph.D. grant SFRH/BD/130458/2017. F.L.S. acknowledges FCT for the researcher contract IF/00222/2015. H.A.S. acknowledges financial support from the HiLIFE Research Funds and the Sigrid Juselius Foundation.