Spherical Cellulose Micro and Nanoparticles: A Review of Recent Developments and Applications
authors Carvalho, JPF; Silva, ACQ; Silvestre, AJD; Freire, CSR; Vilela, C
nationality International
journal NANOMATERIALS
author keywords cellulose; cellulose derivatives; sphere-shaped particles; microparticles; nanoparticles; particle manufacturing; emulsification; microfluidics; nanoprecipitation
keywords DRUG-DELIVERY; CARBOXYMETHYL CELLULOSE; MANUFACTURING PROCESSES; MAGNETIC NANOPARTICLES; ACETATE NANOPARTICLES; CONTROLLED-RELEASE; SUSTAINED-RELEASE; BEADS PREPARATION; IONIC LIQUIDS; MICROSPHERES
abstract Cellulose, the most abundant natural polymer, is a versatile polysaccharide that is being exploited to manufacture innovative blends, composites, and hybrid materials in the form of membranes, films, coatings, hydrogels, and foams, as well as particles at the micro and nano scales. The application fields of cellulose micro and nanoparticles run the gamut from medicine, biology, and environment to electronics and energy. In fact, the number of studies dealing with sphere-shaped micro and nanoparticles based exclusively on cellulose (or its derivatives) or cellulose in combination with other molecules and macromolecules has been steadily increasing in the last five years. Hence, there is a clear need for an up-to-date narrative that gathers the latest advances on this research topic. So, the aim of this review is to portray some of the most recent and relevant developments on the use of cellulose to produce spherical micro- and nano-sized particles. An attempt was made to illustrate the present state of affairs in terms of the go-to strategies (e.g., emulsification processes, nanoprecipitation, microfluidics, and other assembly approaches) for the generation of sphere-shaped particles of cellulose and derivatives thereof. A concise description of the application fields of these cellulose-based spherical micro and nanoparticles is also presented.

publisher MDPI
isbn 2079-4991
year published 2021
volume 11
issue 10
digital object identifier (doi) 10.3390/nano11102744
web of science category 35
subject category Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied
unique article identifier WOS:000714765000001

Sponsors

1suponsers_list_ciceco.jpg