resumo
Two PDMS-SiO2-TiO2-Cao porous hybrid materials were prepared using the same base composition, precursors, and solvents, but following two different sol-gel procedures, based on the authors' previous works where for the first time, in this hybrid system, calcium acetate was used as calcium source. The two different procedures resulted in monolithic materials with different structures, microstructures, and surface wettability. Even though both are highly hydrophobic (contact angles of 127.2 degrees and 150.6 degrees), and present different filling regimes due to different surface topographies, they have demonstrated to be-cytocompatible when tested with human osteoblastic cells, against the accepted idea that high-hydrophobic surfaces are not suitable to cell adhesion and proliferation. At the nanoscale, the existence of hydrophilic silica domains containing calcium, where water molecules are physisorbed, is assumed to support this capability, as discussed. (C) 2016 Elsevier B.V. All rights reserved.
palavras-chave
NUCLEAR-MAGNETIC-RESONANCE; POLYDIMETHYLSILOXANE (PDMS)-CAO-SIO2 HYBRIDS; MESOPOROUS BIOACTIVE GLASSES; SILOXANE-OXIDE MATERIALS; SMALL-ANGLE SCATTERING; SOL-GEL MATERIALS; X-RAY-SCATTERING; STATE SI-29 NMR; CELL-ADHESION; STRUCTURAL-CHARACTERIZATION
categoria
Materials Science
autores
Almeida, JC; Wacha, A; Gomes, PS; Fernandes, MHR; Fernandes, MHV; Salvado, IMM
nossos autores
Isabel Margarida Miranda Salvado
Professor associado
José Carlos Martins de Almeida
Investigador Júnior
Maria Helena Figueira Vaz Fernandes
Professor(a) Jubilado(a)Grupos
G3 - Materiais Eletroquímicos, Interfaces e Revestimentos
G5 - Materiais Biomiméticos, Biológicos e Vivos
agradecimentos
This work was financed by the JECS Trust (Contract 201467), FEDER funds (Program COMPETE) and by FCT funds, by the grant SFRH/BD/72074/2010 and also developed in the scope of the project CICECO-Aveiro Institute of Materials (Ref. FCT UID/CTM/50011/2013), financed by national funds through the FCT/MEC and when applicable co-financed by FEDER under the PT2020 Partnership Agreement.