abstract
Two PDMS-SiO2-TiO2-Cao porous hybrid materials were prepared using the same base composition, precursors, and solvents, but following two different sol-gel procedures, based on the authors' previous works where for the first time, in this hybrid system, calcium acetate was used as calcium source. The two different procedures resulted in monolithic materials with different structures, microstructures, and surface wettability. Even though both are highly hydrophobic (contact angles of 127.2 degrees and 150.6 degrees), and present different filling regimes due to different surface topographies, they have demonstrated to be-cytocompatible when tested with human osteoblastic cells, against the accepted idea that high-hydrophobic surfaces are not suitable to cell adhesion and proliferation. At the nanoscale, the existence of hydrophilic silica domains containing calcium, where water molecules are physisorbed, is assumed to support this capability, as discussed. (C) 2016 Elsevier B.V. All rights reserved.
keywords
NUCLEAR-MAGNETIC-RESONANCE; POLYDIMETHYLSILOXANE (PDMS)-CAO-SIO2 HYBRIDS; MESOPOROUS BIOACTIVE GLASSES; SILOXANE-OXIDE MATERIALS; SMALL-ANGLE SCATTERING; SOL-GEL MATERIALS; X-RAY-SCATTERING; STATE SI-29 NMR; CELL-ADHESION; STRUCTURAL-CHARACTERIZATION
subject category
Materials Science
authors
Almeida, JC; Wacha, A; Gomes, PS; Fernandes, MHR; Fernandes, MHV; Salvado, IMM
our authors
Isabel Margarida Miranda Salvado
Associate Professor
José Carlos Martins de Almeida
Junior Researcher
Maria Helena Figueira Vaz Fernandes
Retired ProfessorGroups
G3 - Electrochemical Materials, Interfaces and Coatings
G5 - Biomimetic, Biological and Living Materials
acknowledgements
This work was financed by the JECS Trust (Contract 201467), FEDER funds (Program COMPETE) and by FCT funds, by the grant SFRH/BD/72074/2010 and also developed in the scope of the project CICECO-Aveiro Institute of Materials (Ref. FCT UID/CTM/50011/2013), financed by national funds through the FCT/MEC and when applicable co-financed by FEDER under the PT2020 Partnership Agreement.