authors |
Almeida, JC; Wacha, A; Gomes, PS; Fernandes, MHR; Fernandes, MHV; Salvado, IMM |
nationality |
International |
journal |
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS |
author keywords |
Sol-gel; Hybrid materials; Hydrophobicity; Cytocompatibility; Bone |
keywords |
NUCLEAR-MAGNETIC-RESONANCE; POLYDIMETHYLSILOXANE (PDMS)-CAO-SIO2 HYBRIDS; MESOPOROUS BIOACTIVE GLASSES; SILOXANE-OXIDE MATERIALS; SMALL-ANGLE SCATTERING; SOL-GEL MATERIALS; X-RAY-SCATTERING; STATE SI-29 NMR; CELL-ADHESION; STRUCTURAL-CHARACTERIZATION |
abstract |
Two PDMS-SiO2-TiO2-Cao porous hybrid materials were prepared using the same base composition, precursors, and solvents, but following two different sol-gel procedures, based on the authors' previous works where for the first time, in this hybrid system, calcium acetate was used as calcium source. The two different procedures resulted in monolithic materials with different structures, microstructures, and surface wettability. Even though both are highly hydrophobic (contact angles of 127.2 degrees and 150.6 degrees), and present different filling regimes due to different surface topographies, they have demonstrated to be-cytocompatible when tested with human osteoblastic cells, against the accepted idea that high-hydrophobic surfaces are not suitable to cell adhesion and proliferation. At the nanoscale, the existence of hydrophilic silica domains containing calcium, where water molecules are physisorbed, is assumed to support this capability, as discussed. (C) 2016 Elsevier B.V. All rights reserved. |
publisher |
ELSEVIER SCIENCE BV |
issn |
0928-4931 |
year published |
2016 |
volume |
64 |
beginning page |
74 |
ending page |
86 |
digital object identifier (doi) |
10.1016/j.msec.2016.03.071 |
web of science category |
Materials Science, Biomaterials |
subject category |
Materials Science |
unique article identifier |
WOS:000376547700009
|
ciceco authors
impact metrics
journal analysis (jcr 2019):
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journal impact factor |
5.88 |
5 year journal impact factor |
5.364 |
category normalized journal impact factor percentile |
82.895 |
dimensions (citation analysis):
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altmetrics (social interaction):
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