Solvent Properties Governing Solute Partitioning in Polymer/Polymer Aqueous Two-Phase Systems: Nonionic Compounds

resumo

The solvatochromic solvent parameters characterizing the solvent polarity (pi*), solvent hydrogen-bond donor acidity (alpha), and solvent hydrogen-bond acceptor basicity (beta) of aqueous media were measured in the coexisting phases of nine different aqueous polymer/polymer two-phase systems (ATPS), containing 0.15 M NaCl in 0.01 M phosphate buffer, pH 7.4. Partitioning coefficients of six neutral compounds were measured in the nine ATPS at particular polymer Concentrations. The solvatochromic equation was used to describe the partitioning of each Compound. Three descriptors of the solvent properties of the phases Could describe adequately the partitioning of the solutes in all the ATPS employed.

palavras-chave

SOLVATOCHROMIC COMPARISON METHOD; SOLVATION ENERGY RELATIONSHIPS; BIPHASIC SYSTEMS; POLY(ETHYLENE GLYCOL); POLYETHYLENE-GLYCOL; ORGANIC-MOLECULES; METHYLENE GROUP; PI-STAR; ALPHA; SCALE

categoria

Chemistry

autores

Madeira, PP; Reis, CA; Rodrigues, AE; Mikheeva, LM; Zaslavsky, BY

nossos autores

agradecimentos

We thank Professor A H. Abraham (University College London) for helpful discussions and for reviewing the manuscript. PPM acknowledges Prof. Eugenia Macedo (LSRE-Porto) for the use of her equipment to measure solvatochromic data. P.P.M. acknowledges financial Support (Grant SFRH/BPD/45055/2008) from Fundacao Para a Ciencia e a Tecnologia (FCT), Lisbon, Portugal.

Partilhe este projeto

Publicações similares

Usamos cookies para atividades de marketing e para lhe oferecer uma melhor experiência de navegação. Ao clicar em “Aceitar Cookies” você concorda com nossa política de cookies. Leia sobre como usamos cookies clicando em "Política de Privacidade e Cookies".