Exploring Anticancer and (Bio)catalytic Activities of New Oxovanadium(V), Dioxomolybdenum(VI), and Copper(II) Complexes of Amide-Imine Conjugates


An amide-imine conjugate, (E)-N_-((2-hydroxynaphthalen-1-yl) methylene)-4-methylbenzohydrazide (PTANAP), derived from 4-methyl-benzoic acid hydrazide (PTA) and 2-hydroxynapthaldehyde, is explored to prepare dinuclear oxovanadium(V), mononuclear dioxomolydenum(VI), and Cu(II) complexes. Single crystal X-ray structurally characterized complexes have been exploited as catalyst for oxidation of ethylbenzene, catechol, and o-aminophenol. The anticancer properties of the oxo-vanadium complex have been explored against human leukemia cell (K-562) and mouse lymphoma cells (2PK3). © 2019 American Chemical Society.


Ta S.; Ghosh M.; Ghosh K.; Branda› P.; FŽlix V.; Hira S.K.; Manna P.P.; Das D.

nossos autores


M.G. gratefully acknowledges CSIR (New Delhi) for funding. K.G. acknowledges Department of Science & Technology (New Delhi) for NPDF PDF/2016/000160). S.K.H. acknowledge Subhadip Bhowmik, USIC, BU (for Multiskan GO facility), DST (FIST and PURSE) programs for research facilities and also acknowledges DST-SERB, New Delhi, India (No. EEQ/2017/0076) for partial financial support. Crystallographic studies have been performed out of the project CICECO-Aveiro Institute of Materials, FCT ref. UID/CTM/50011/2019, financed by national funds through the FCT/MCTES.

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