resumo
Diamond-based electrodes and biosensors are interesting in analytics because of their particular set of properties, namely: large potential window, chemical inertness, low baseline current, stability, and transparency. Diamond-based electrodes and biosensors were shown to detect biological molecules such as neurotransmitters and proteins, respectively. In this review, we summarise the different types of diamond electrodes and biosensors based on their type of detection (electrochemical or optical), functionalisation, and target analyte. The last section presents a discussion on the different analytical responses obtained with electrodes or biosensors, according to the type of analyte. Electrodes work quite well for detecting small molecules with redox properties, whereas biosensors are more suited for detecting molecules with a high molecular weight, such as DNA and proteins.
palavras-chave
SURFACE FUNCTIONALIZATION; ELECTROCHEMICAL OXIDATION; AMPEROMETRIC DETECTION; BIOSENSING PROPERTIES; INFLUENZA-VIRUS; DNA ATTACHMENT; THIN-FILMS; BORON; ELECTRODES; DOPAMINE
categoria
Chemistry; Engineering; Materials Science; Physics
autores
Santos, NE; Figueira, F; Neto, M; Paz, FAA; Braga, SS; Mendes, JC
nossos autores
Filipe Alexandre Almeida Paz
Investigador Principal
Flávio Alberto da Silva Figueira
Investigador Júnior
Miguel Ângelo da Costa Neto
Investigador
Susana Isabel Fonseca de Almeida Santos Braga
InvestigadorGrupos
G1 - Materiais Porosos e Nanossistemas
G3 - Materiais Eletroquímicos, Interfaces e Revestimentos
Projectos
CICECO - Aveiro Institute of Materials (UIDB/50011/2020)
CICECO - Aveiro Institute of Materials (UIDP/50011/2020)
Associated Laboratory CICECO-Aveiro Institute of Materials (LA/P/0006/2020)
agradecimentos
We acknowledge University of Aveiro and FCT/MCTES (Fundacao para a Ciencia e a Tecnologia, Ministerio da Ciencia, da Tecnologia e do Ensino Superior) for financial support to LAQV-REQUIMTE (Ref. UIDB/50006/2020), and to CICECO-Aveiro Institute of Materials (Refs. UIDB/50011/2020, UIDP/50011/2020 & LA/P/0006/2020) through national founds (PIDDAC) and, where applicable, co-financed by the European Regional Development Fund (FEDER), within the PT2020 Partnership Agreement. The work of Instituto de Telecomunicacoes is funded by FCT/MCTES through national funds and when applicable co-funded EU funds under the project UIDB/50008/2020-UIDP/50008/2020. The research contract of FF (REF-168-89-ARH/2018) is funded by national funds (OE), through FCT, in the scope of the framework contract foreseen in Nos. 4, 5 and 6 of article 23 of the Decree-Law 57/2016, of 29 August, changed by Law 57/2017, of 19 July.