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Susana Isabel Fonseca de Almeida Santos Braga
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Investigador
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telefone:
234 401 418 |
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extensão:
24 918 |
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e-mail:
sbraga@ua.pt |
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departamento:
Química |
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Licenciada em Ciéncias Farmaceuticas pela Universidade do Porto em 1998 e Doutora em Química pela Universidade de Aveiro em 2003. Desenvolveu estudos em sistemas supramoleculares hóspede-hospedeiro baseados em ciclodextrinas e especies organicas e metalo-orgânicas de interesse farmacológico.
Nos ultimos cinco anos, foram desenvolvidos novos complexos de coordinação de ruténio, cobre e európio para aplicação em quimioterapia, desinfecção de superfícies e electrónica.
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I. Ciclodextrinas como capsulas moleculares de nanométricas para
i. antitumorais biomiméticos de Ru(II)
ii. agentes antimicrobianos
iii. complexos organometálicos funcionais
II. Ciclodextrinas como veículos e estabilisantes de formulações
i. com oleo de thymus spp
ii. com oleo de occimum basilicum
III. Ciclodextrinas como isoladores eléctricos moleculares para compostos emissores de luz
i. complexos de lantanídeos
ii. corantes naturais funcionalizados com Ru(II)
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FCT
POCI/SAU/BEB/66869/2006
PDTC/QUI/69302/2006
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1. A potentiometric biosensor for D-amygdaline based on a consolidated biocomposite membrane
Arben Merkoçi, Susana Braga, Esteve Fàbregas, Salvador Alegret, Anal. Chim. Acta 391 (1999) 65-72
2. Encapsulation of half sandwich complexes of molybdenium with beta-cyclodextrin
Susana S. Braga, Isabel S. Gonçalves, André D. Lopes, Martyn Pillinger, João Rocha, Carlos C. Romão, José J.C. Teixeira-Dias, J. Chem. Soc. Dalton Trans. (2000) 2963-2968
3. Experimental and theoretical study of the interaction of molybdenocene dichloride (Cp2MoCl2) with beta-cyclodextrin
Susana S. Braga, Isabel S. Gonçalves, Martyn Pillinger, Paulo Ribeiro-Claro, José J.C. Teixeira-Dias, J. Organom. Chem. (2001) 11-16
4. Encapsulation of cyano(cyclopentadienyl) complexes of iron with beta-cyclodextrin
Susana S. Braga, Isabel S. Gonçalves, Paulo Ribeiro-Claro, André D. Lopes, Martyn Pillinger, José J.C. Teixeira-Dias, João Rocha, Carlos C. Romão, Supramol. Chem. 14 (2002) 359-366
5. Structure of the beta-Cyclodextrin.p-Hydroxybenzaldehyde Inclusion Complex in Aqueous Solution and in the Crystalline State
Susana S. Braga, Thammarat Aree, Kayo Imamura, Pierre Vertut, Isabel Boal-Palheiros, Wolfram Saenger, José J.C. Teixeira-Dias, J. Incl. Phenom. Macro. Chem. 43 (2002) 115-125
6. Synthesis, characterization and luminescence of beta-cyclodextrin inclusion compounds containing europium (III) and gadolinium (III) tris(beta-diketonates) Susana S. Braga, Rute A.S. Ferreira, Isabel S. Gonçalves, Martyn Pillinger, João Rocha, José J.C. Teixeira-Dias, Luís D. Carlos, J. Phys. Chem. B 106 (2002) 11430-11437
7. Study of the inclusion compound formed between a luminescent europium (III) beta-diketonate complex and gamma-cyclodextrin
Susana S. Braga, Rute A. S. Ferreira, Isabel S. Gonçalves, Paulo Ribeiro-Claro, Martyn Pillinger, João Rocha, José J.C. Teixeira-Dias, Luís D. Carlos, J. Incl. Phenom. Macro. Chem. 44 (2002) 261-265
8. Solid State Inclusion Compound of S-Ibuprofen in beta-Cyclodextrin: Structure and Characterization
Susana S. Braga, Isabel S. Gonçalves, Eberdardt Herdtweck, José J.C. Teixeira-Dias, New J. Chem. 27 (2003) 597-601
9. Encapsulation of sodium nimesulide and precursors in beta-cyclodextrin Susana S. Braga, Paulo Ribeiro-Claro, Martyn Pillinger, Isabel S. Gonçalves, Florbela Pereira, Ana C. Fernandes, Carlos C. Romão, Pedro B. Correia, José J.C. Teixeira-Dias, Org. Biomol. Chem. 1 (2003) 873-878
10. Interactions of Omeprazole and Precursors with beta-Cyclodextrin Host Molecules
Susana S. Braga, Paulo Ribeiro-Claro, Martyn Pillinger, Isabel S. Gonçalves, Ana C. Fernandes, Florbela Pereira, Carlos C. Romão, Pedro B. Correia, José J.C. Teixeira-Dias, J. Incl. Phenom. Macro. Chem. 47 (2003) 47-52.
11. Synthesis of ferrocenyldiimine metal carbonyl complexes and an investigation of the Mo adduct encapsulated in cyclodextrin
Željko Petrovski, Susana S. Braga, Sandra S. Rodrigues, Cláudia C. L. Pereira, Isabel S. Gonçalves, Martyn Pillinger, Cristina Freire, Carlos C. Romão, New J. Chem. 29 (2005) 347–354
12. Synthesis and characterization of the inclusion compound of a ferrocenyldiimine dioxomolybdenum complex with heptakis-2,3,6-tri-O-methyl-beta-cyclodextrin
Željko Petrovski, Susana S. Braga, Ana M. Santos, Sandra S. Rodrigues, Isabel S. Gonçalves, Martyn Pillinger, Fritz E. Kühn, Carlos C. Romão, Inorg. Chim. Acta 358 (2005) 981-988.
13. Inclusion of molybdenocene dichloride (Cp2MoCl2) in 2-hydroxypropyl- and trimethyl-beta-cyclodextrin: structural and biological properties
Susana S. Braga, Maria P.M. Marques, Joana B. Sousa, Martyn Pillinger, José J.C. Teixeira-Dias, Isabel S. Gonçalves, J. Organomet. Chem. 690 (2005) 2905-2912
14. Inclusion complex formation of diferrocenyldimethylsilane with beta-cyclodextrin
José A. Fernandes, Sérgio Lima, Susana S. Braga, Paulo Ribeiro-Claro, José E. Rodriguez-Borges, Cátia Teixeira, Martyn Pillinger, José J.C. Teixeira-Dias, Isabel S. Gonçalves, J. Organomet. Chem. 690 (2005) 4801-4808.
15. Inclusion complexation of dimeric and trimeric oligo(ferrocenyl-dimethylsilanes) with gamma-cyclodextrin
José A. Fernandes, Sérgio Lima, Susana S. Braga, Martyn Pillinger, Paulo Ribeiro-Claro, José E. Rodriguez-Borges, André D. Lopes, José J. C. Teixeira-Dias, Isabel S. Gonçalves, Organometallics 24 (2005) 5673-5677.
16. Experimental and theoretical study of the encapsulation of a linear oligo(ferrocenyl-silane) trimer with beta-cyclodextrin
José A. Fernandes, Sérgio Lima, Susana S. Braga, Martyn Pillinger, José E. Rodríguez-Borges, Paulo Ribeiro-Claro, José J. C. Teixeira-Dias, Isabel S. Gonçalves, Eur. J. Inorg. Chem. 23 (2005) 4729-4734.
17. Beta-cyclodextrin inclusion of europium(III) tris(beta-diketonate)-bipyridine José A. Fernandes, Susana S. Braga, Martyn Pillinger, Rute A. S. Ferreira, Luís D. Carlos, Alan Hazell, Josua Jepsen, Paulo Ribeiro-Claro, Isabel S. Gonçalves, Polyhedron 25 (2006) 1471-1476.
18. Modification of the luminescence properties of a europium(III) tris(beta-diketonate) complex by inclusion in gamma-cyclodextrin and 2,3,6-trimethyl-gamma-cyclodextrin
José A. Fernandes, Susana S. Braga, Rute A. Sá Ferreira, Martyn Pillinger, Luís D. Carlos, Paulo Ribeiro-Claro, Isabel S. Gonçalves, J. Inc. Phenom Macro. Chem. 55 (2006) 329-333.
19. Structural Studies of beta-Cyclodextrin and Permethylated beta-Cyclodextrin Inclusion Compounds of Cyclopentadienyl Metal Carbonyl Complexes
Susana S. Braga, Filipe A.A. Paz, Martyn Pillinger, João D. Seixas, Carlos C. Romão, Isabel S. Gonçalves, Eur. J. Inorg. Chem. (2006) 1662-1669.
20. Structure of Cyclopentadienyl Molybdenum Carbonyl Complexes bearing acetonitrile and bis-imine ligands and their Encapsulation in Cyclodextrins Claudia C.L. Pereira, Susana S. Braga, Filipe A. Almeida Paz, Martyn Pillinger, Jacek Klinowski, Isabel S. Gonçalves, Eur. J. Inorg. Chem (2006) 4278-4288.
21. beta-Cyclodextrin and permethylated beta-cyclodextrin inclusion compounds of a cyclopentadienyl molybdenum tricarbonyl complex and their use as cyclooctene epoxidation catalyst precursors
Susana S. Braga, Sandra Gago, João D. Seixas, Anabela A. Valente, Martyn Pillinger, Teresa M. Santos, Isabel S. Gonçalves, Carlos C. Romão, Inorg. Chim. Acta 359 (2006) 4757-4764.
22. Influence of cyclodextrins on catalytic olefin epoxidation with metal-carbonyl compounds. Crystal structure of the TRIMEB complex with CpFe(CO)(2)Cl
Salete S. Balula, Ana C. Coelho, Susana S. Braga, Alan Hazell, Anabela A. Valente, Martyn Pillinger, Joao D. Seixas, Carlos C. Romão), Isabel S. Goncalves, Organometallics 26 (2007) 6857-6863.
23. (2,2\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'-bipyridine)tetracarbonylmolybdenum(0)
Susana S. Braga, Ana C. Coelho, Isabel S. Goncalves, Filipe A. Almeida Paz, Acta Crystallogr. E - Struct. Rep. Online 62 (2007) m780-m782.
24. A combined theoretical-experimental study of the inclusion of niobocene dichloride in native and permethylated beta-cyclodextrins
Claudia C. L. Pereira, Mariela Nolasco, Susana S. Braga, Filipe A. Almeida Paz, Paulo Ribeiro-claro, Martyn Pillinger, Isabel S. Goncalves, organometallics 26 (2007) 4220-4228.
25. Cyclodextrin encapsulation of biomimetic organometallic cancer drug candidates
Susana S. Braga, Filipe A. Almeida Paz, Vijaya Mokal, Martyn Pillinger, Maria Paula M. Marques, Carlos C. Romão, Isabel S. Goncalves, Drugs Futur. 23 Suppl. A (2007) 101.
26. Synthesis, characterization and antitumour activity of 1,2-disubstituted ferrocenes and cyclodextrin inclusion complexes
Željko Petrovski, Marta R. P. N. de Matos, Susana S. Braga, Claudia C. L. Pereira, Marcia L. Matos, Isabel S. Goncalves, Martyn Pillinger, Paula M. Alves, Carlos C. Romão, J. Organomet. Chem. 693 (2008) 675-684.
27. Luminescence properties of the TRIMEB inclusion compound of a europium tris-β-diketonate
Susana S. Braga, Ana C. Coelho, Isabel S. Gonçalves, Gerson Santos, Fernando J. Fonseca, A. M. Andrade, Marco Peres, Wilson Simões, Teresa Monteiro, Luiz Pereira, J. Non-Cryst. Solids 354 (2008) 2736-2739.
28. Organic light emitting diodes with europium (III) emissive layers based on β-diketonate complexes: The influence of the central ligand
Gerson Santos, Fernando J. Fonseca, A. M. Andrade, V. Deichmann, L. Akcelrud, Susana S. Braga, Ana C. Coelho, Isabel S. Gonçalves, Marco Peres, Wilson Simões, Teresa Monteiro, Luiz Pereira, J. Non-Cryst. Solids 354 (2008) 2897-2900.
29. Structural Studies on Supramolecular Adducts of Cyclodextrins with the Complex [Ru([9]aneS3)(bpy)Cl]Cl
Joana Marques, Lúcia Anjo, Maria Paula M. Marques, Teresa M. Santos, Filipe A. Almeida Paz, Susana S. Braga, J. Organomet. Chem. 693 (2008) 3021-3028.
30. Complex Formation Between Heptakis(2,6-di-O-methyl)-ß-cyclodextrin and Cyclopentadienyl Molybdenum(II) Dicarbonyl complexes: Structural Studies and Cytotoxicity Evaluations
Cláudia C.L. Pereira, Cátia V. Diogo, Ana Burgeiro, Paulo J. Oliveira, Maria Paula M. Marques, Susana S. Braga, Filipe A. Almeida Paz, Martyn Pillinger, Isabel S. Gonçalves, Organometallics 27 (2008) 4948-4956.
31. Cyclodextrins improve the Antimicrobial Activity of the chloride salt of Ruthenium(II) Chloro-phenanthroline-trithiacyclononane
Joana Marques, Teresa M. Braga, Filipe A. Almeida Paz, Teresa M. Santos, Maria de Fátima Silva Lopes, Susana S. Braga, Biometals 22 (2009) 541-556.
23. Triclosan
Ana I. Ramos, Susana S. Braga, Filipe A. Almeida Paz, Acta Cryst. C65 (2009) o404-o405.
33. A glycine ruthenium trithiacyclononane complex and its molecular encapsulation using cyclodextrins
Joana Marques, Teresa M. Santos, Maria Paula Marques, Susana S. Braga, Dalton Trans. (2009) 9812-9819.
34. Diaquabis(ethylenediamine-κ2NN\\\\\\\\\\\\\\\\\\\\\\\')Copper(II) Bis(4-phenylbenzoate) 2.66-hydrate
José A. Fernandes, Ana I. Ramos, Patrícia Silva, Susana S. Braga, Paulo Ribeiro-Claro, João Rocha, Filipe A. Almeida Paz, Acta Cryst. E66 (2010) m626-m627.
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Bisphosphonates, Old Friends of Bones and New Trends in ClinicsBarbosa, JS; Paz, FAA; Braga, SS
2021, JOURNAL OF MEDICINAL CHEMISTRY, 64, 3, 1260-1282.
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Cyclodextrins in Antiviral Therapeutics and VaccinesBraga, SS; Barbosa, JS; Santos, NE; El-Saleh, F; Paz, FAA
2021, PHARMACEUTICS, 13, 3,
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Inclusion Compound of Efavirenz and gamma-Cyclodextrin: Solid State Studies and Effect on SolubilityBraga, SS; El-Saleh, F; Lysenko, K; Paz, FAA
2021, MOLECULES, 26, 3,
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Empowering the Medicinal Applications of Bisphosphonates by Unveiling their Synthesis DetailsBarbosa, JS; Braga, SS; Paz, FAA
2020, MOLECULES, 25, 12,
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Natural and Biomimetic Antitumor Pyrazoles, A PerspectiveSantos, NE; Carreira, ARF; Silva, VLM; Braga, SS
2020, MOLECULES, 25, 6,
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Solid gamma-Cyclodextrin Inclusion Compound with Gingerols, a Multi-Component Guest: Preparation, Properties and Application in YogurtPais, JM; Pereira, B; Paz, FAA; Cardoso, SM; Braga, SS
2020, BIOMOLECULES, 10, 2,
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Preformulation Studies of the gamma-Cyclodextrin and Montelukast Inclusion Compound Prepared by ComillingBarbosa, JS; Nolasco, MM; Ribeiro-Claro, P; Paz, FAA; Braga, SS
2019, JOURNAL OF PHARMACEUTICAL SCIENCES, 108, 5, 1837-1847.
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Association of aescin with beta- and gamma-cyclodextrins studied by DFT calculations and spectroscopic methodsRamos, AI; Vaz, PD; Braga, SS; Silva, AMS
2017, BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 8, 348-357.
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Supramolecular adducts of native and permethylated beta-cyclodextrins with (2,2'-dipyridylamine)chlorido(1,4,7-trithiacyclononane)ruthenium(II) chloride: solid-state and biological activity studiesBraga, SS; Marques, J; Fernandes, JA; Paz, FAA; Marques, MPM; Santos, TM; Silva, AMS
2017, CHEMICAL PAPERS, 71, 7, 1235-1248.
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Solid-state studies and antioxidant properties of the gamma-cyclodextrin fisetin inclusion compoundPais, JM; Barroca, MJ; Marques, MPM; Paz, FAA; Braga, SS
2017, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 13, 2138-2145.
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Montelukast medicines of today and tomorrow: from molecular pharmaceutics to technological formulationsBarbosa, JS; Paz, FAA; Braga, SS
2016, DRUG DELIVERY, 23, 9, 3257-3265.
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Studies on polymorph conversion in a new cyclodextrin inclusion compoundFernandes, JA; Ramos, AI; Ribeiro-Claro, P; Paz, FAA; Braga, SS
2015, CRYSTENGCOMM, 17, 4, 937-946.
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Crystal Structure and Spectroscopic Studies of a Dimeric Europium( III) similar to- Diketonate Complex Containing [ 3-( 2-Pyridyl)-1-pyrazolyl] acetateCoelho, AC; Gomes, AC; Fernandes, JA; Paz, FAA; Braga, SS; Rino, L; Pereira, L; Pillinger, M; Goncalves, IS
2014, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2014, 8, 1284-1288.
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Carriers for metal complexes on tumour cells: the effect of cyclodextrins vs CNTs on the model guest phenanthroline-5,6-dione trithiacyclononane ruthenium(II) chlorideBraga, SS; Marques, J; Heister, E; Diogo, CV; Oliveira, PJ; Paz, FAA; Santos, TM; Marques, MPM
2014, BIOMETALS, 27, 3, 507-525.
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Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(cyclopentadienyl)molybdenum Complexes and Cyclodextrin Inclusion CompoundsBraga, SS; Mokal, V; Paz, FAA; Pillinger, M; Branco, AF; Sardao, VA; Diogo, CV; Oliveira, PJ; Marques, MPM; Romao, CC; Goncalves, IS
2014, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 29, 5034-5045.
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Shaping Cytotoxicity of Organometallics and Complex Antitumorals via Molecular EncapsulationFilipe A. Almeida Paz and Susana S. Braga
In H. F. Chin (Eds.), Organometallic Compounds: Preparation, Structure and Properties
2011, 465-481. Hauppauge, New York: Nova Science Publishers, Inc..
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Shaping Cytotoxicity of Organometallics and Complex Antitumorals via Molecular EncapsulationPaz F A A, Braga SS
In H. F. Chin, Hauppauge (Eds.), Organometallic Compounds: Preparation, Structure and Properties
2010, 465-481. New York: Nova Science Publishers.
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