Biofunctionalized ferromagnetic CoPt3/polymer nanocomposites
authors Martins, MA; Neves, MC; Esteves, ACC; Girginova, PI; Guiomar, AJ; Amaral, VS; Trindade, T
nationality International
journal NANOTECHNOLOGY
keywords IRON-OXIDE NANOPARTICLES; MAGNETIC POLYMER NANOSPHERES; MINIEMULSION POLYMERIZATION; BIOMEDICAL APPLICATIONS; QUANTUM DOTS; INORGANIC PARTICLES; SEMICONDUCTOR NANOCRYSTALS; SURFACE MODIFICATION; POLYSTYRENE LATEX; ENCAPSULATION
abstract Magnetic latexes were prepared by the encapsulation of organically capped CoPt3 nanoparticles via miniemulsion in situ radical polymerization of tert-butyl acrylate (tBA). This is the first example of a CoPt3 based polymer nanocomposite showing ferromagnetic behaviour at room temperature. Each nanocomposite particle contains a magnetic core composed of CoPt3 nanoparticles (d similar to 7 nm, a(0) = 3.848 angstrom) encapsulated by poly(t-butyl acrylate). The CoPt3/PtBA latexes contain polyester groups that can be readily hydrolysed, rendering the surface with carboxylic functionalities and hence allowing bioconjugation. Complementary to such surface modification experiments, we report that bovine IgG antibodies can bind to the magnetic latexes, and the potential of the nanocomposites for in vitro specific bioapplications is discussed.
publisher IOP PUBLISHING LTD
issn 0957-4484
year published 2007
volume 18
issue 21
digital object identifier (doi) 10.1088/0957-4484/18/21/215609
web of science category Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied
subject category Science & Technology - Other Topics; Materials Science; Physics
unique article identifier WOS:000246590200018
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journal analysis (jcr 2019):
journal impact factor 3.551
5 year journal impact factor 3.392
category normalized journal impact factor percentile 63.589
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