Biofunctionalized ferromagnetic CoPt3/polymer nanocomposites

authors	Martins, MA; Neves, MC; Esteves, ACC; Girginova, PI; Guiomar, AJ; Amaral, VS; Trindade, T
nationality	International
journal	NANOTECHNOLOGY
keywords	IRON-OXIDE NANOPARTICLES; MAGNETIC POLYMER NANOSPHERES; MINIEMULSION POLYMERIZATION; BIOMEDICAL APPLICATIONS; QUANTUM DOTS; INORGANIC PARTICLES; SEMICONDUCTOR NANOCRYSTALS; SURFACE MODIFICATION; POLYSTYRENE LATEX; ENCAPSULATION
abstract	Magnetic latexes were prepared by the encapsulation of organically capped CoPt3 nanoparticles via miniemulsion in situ radical polymerization of tert-butyl acrylate (tBA). This is the first example of a CoPt3 based polymer nanocomposite showing ferromagnetic behaviour at room temperature. Each nanocomposite particle contains a magnetic core composed of CoPt3 nanoparticles (d similar to 7 nm, a(0) = 3.848 angstrom) encapsulated by poly(t-butyl acrylate). The CoPt3/PtBA latexes contain polyester groups that can be readily hydrolysed, rendering the surface with carboxylic functionalities and hence allowing bioconjugation. Complementary to such surface modification experiments, we report that bovine IgG antibodies can bind to the magnetic latexes, and the potential of the nanocomposites for in vitro specific bioapplications is discussed.
publisher	IOP PUBLISHING LTD
issn	0957-4484
year published	2007
volume	18
issue	21
digital object identifier (doi)	10.1088/0957-4484/18/21/215609
web of science category	Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied
subject category	Science & Technology - Other Topics; Materials Science; Physics
unique article identifier	WOS:000246590200018