resumo
A new approach to the synthesis of multifunctional nanoparticles was developed by using covalent anchoring of cyano-bridged coordination polymer Ni(2+)/[Fe(CN)(6)](3-) to the surface of two-photon dyedoped mesoporous silica nanoparticles. The obtained hybrid nanoparticles were studied by infrared (IR) spectroscopy, nitrogen adsorption (BET), X-ray diffraction, transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), luminescence, and magnetic analysis. The synthesis leads to homogeneously dispersed uni-shaped nanoparticles of around 100 nm in length that are coated with cyano-bridged metallic coordination polymer nanoparticles. These hybrid nanoparticles combine effective two-photon excited fluorescence, porosity, high transverse nuclear relaxivity values (i.e. the magnetic resonance imaging efficiency) and superparamagnetic properties.
palavras-chave
COORDINATION POLYMER NANOPARTICLES; METAL-ORGANIC FRAMEWORKS; SPIN-GLASS; MULTIFUNCTIONAL NANOPARTICLES; CANCER-CELLS; NANOMEDICINE APPLICATIONS; HYBRID NANOPARTICLES; DESIGNED FABRICATION; PHOTOTHERMAL THERAPY; GOLD NANOSHELLS
categoria
Chemistry; Materials Science
autores
Chelebaeva, E; Raehm, L; Durand, JO; Guari, Y; Larionova, J; Guerin, C; Trifonov, A; Willinger, M; Thangavel, K; Lascialfari, A; Mongin, O; Mir, Y; Blanchard-Desce, M
Grupos
agradecimentos
The authors thank Mme Corine Rebeil (UM2, Institute Charles Gerhardt Montpellier, France) for magnetic measurements. The authors also thank the CNRS, the Universite Montpellier II and the network of excellence MAGMANet (FP6-NMP3-CT-2005-515767) for financial support as well as the Portuguese network of electron microscopy, the RNME, FCT Project: REDE/1509/RME/2005.