Born on 22 of June of 1991 at Aveiro, Portugal, João Santos obtained her MSc degree in Biotechnology from University of Aveiro, Portugal, in 2014. During his graduation Santos was awarded with a research grant (Santander-Universities Scholarship Programme) and in the last year of the MSc studies joined to the Process and Product Applied Thermodynamics (PATh) research group, where he developed her MSc thesis within the topic "Designing new downstream processes based in FPLC and ABS methodologies”. João Santos is currently a PhD student in Chemical Engineering at the University of Aveiro, Portugal, working on the development of novel downstream processes using aqueous biphasic systems technology and in the PEGylation field for biopharmaceutical and biosensing proposes. In his PhD he is working in close colaboration with Pharmaceutical Sciencies Department at University of São Paulo (USP), conducted a 1-year period of exchange at Laboratory of Nanobiotechnology in USP.
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Purification of Pseudomonas sp. proteases through aqueous biphasic systems as an alternative source to obtain bioactive protein hydrolysatesPillaca-Pullo, OS; Intiquilla, A; Santos, JHPM; Sanchez-Moguel, I; Brandelli, A; Zavaleta, AI 2021, BIOTECHNOLOGY PROGRESS, 37, 3,
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Sustainable Strategy Based on Induced Precipitation for the Purification of PhycobiliproteinsMartins, M; Soares, BP; Santos, JHPM; Bharmoria, P; Acosta, MAT; Dias, ACRV; Coutinho, JAP; Ventura, SPM 2021, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 9, 10, 3942-3954.
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Purification of green fluorescent protein using fast centrifugal partition chromatographySoares, BP; Santos, JHPM; Martins, M; Almeida, MR; Santos, NV; Freire, MG; Santos-Ebinuma, VC; Coutinho, JAP; Pereira, JFB; Ventura, SPM 2021, SEPARATION AND PURIFICATION TECHNOLOGY, 257,
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Characterization of levan produced by a Paenibacillus sp. isolated from Brazilian crude oilMendonca, CMN; Oliveira, RC; Freire, RKB; Piazentin, ACM; Pereira, WA; Gudina, EJ; Evtuguin, DV; Converti, A; Santos, JHPM; Nunes, C; Rodrigues, LR; Oliveira, RPS 2021, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 186, 788-799.
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Controlling the l-asparaginase extraction and purification by the appropriate selection of polymer/salt-based aqueous biphasic systemsMagri, A; Pimenta, MV; Santos, JHPM; Coutinho, JAP; Ventura, SPM; Monteiro, G; Rangel-Yagui, CO; Pereira, JFB 2020, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 95, 4, 1016-1027.
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Imidazolium-based Ionic Liquids as Adjuvants to Form Polyethylene Glycol with Salt Buffer Aqueous Biphasic SystemsSantos, JHPM; Martins, M; Silva, ARP; Cunha, JR; Rangel-Yagui, CO; Ventura, SPM 2020, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 65, 8, 3794-3801.
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Continuous separation of cytochrome-c PEGylated conjugates by fast centrifugal partition chromatographySantos, JHPM; Ferreira, AM; Almeida, MR; Quinteiro, PSGN; Dias, ACRV; Coutinho, JAP; Freire, MG; Rangel-Yagui, CO; Ventura, SPM 2019, GREEN CHEMISTRY, 21, 20, 5501-5506.
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An integrated process combining the reaction and purification of PEGylated proteinsSantos, JHPM; Mendonca, CMN; Silva, ARP; Oliveira, RPS; Pessoa, A; Coutinho, JAP; Ventura, SPM; Rangel-Yagui, CO 2019, GREEN CHEMISTRY, 21, 23, 6407-6418.
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Novel site-specific PEGylated L-asparaginaseMeneguetti, GP; Santos, JHPM; Obreque, KMT; Barbosa, CMV; Monteiro, G; Farsky, SHP; de Oliveira, AM; Angeli, CB; Palmisano, G; Ventura, SPM; Pessoa, A; Rangel-Yagui, CD 2019, PLOS ONE, 14, 2,
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PEGylation as an efficient tool to enhance cytochrome c thermostability: a kinetic and thermodynamic studySantos, JHPM; Carretero, G; Ventura, SPM; Converti, A; Rangel-Yagui, CO 2019, JOURNAL OF MATERIALS CHEMISTRY B, 7, 28, 4432-4439.
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Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality ProfilesBrumano, LP; da Silva, FVS; Costa-Silva, TA; Apolinario, AC; Santos, JHPM; Kleingesinds, EK; Monteiro, G; Rangel-Yagui, CD; Benyahia, B; Pessoa, A 2019, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 6,
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In situ purification of periplasmatic L-asparaginase by aqueous two phase systems with ionic liquids (ILs) as adjuvantsSantos, JHPM; Flores-Santos, JC; Meneguetti, GP; Rangel-Yagui, CO; Coutinho, JAP; Vitolo, M; Ventura, SPM; Pessoa, A 2018, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 93, 7, 1871-1880.
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Separation of phenolic compounds by centrifugal partition chromatographySantos, JHPM; Almeida, MR; Martins, CIR; Dias, ACRV; Freire, MG; Coutinho, JAP; Ventura, SPM 2018, GREEN CHEMISTRY, 20, 8, 1906-1916.
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Aqueous biphasic systems in the separation of food colorantsSantos, JHPM; Capela, EV; Boal-Palheiros, I; Coutinho, JAP; Freire, MG; Ventura, SPM 2018, BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, 46, 4, 390-397.
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Fractionation of Isochrysis galbana Proteins, Arabinans, and Glucans Using Ionic-Liquid-Based Aqueous Biphasic SystemsSantos, JHPM; Trigo, JP; Maricato, E; Nunes, C; Coimbra, MA; Ventura, SPM 2018, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 6, 11, 14042-14053.
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