João Henrique Picado Madalena Santos

PhD Student

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Department

  • Chemistry

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Short CV

Born on 22 of June of 1991 at Aveiro, Portugal, João Santos obtained her MSc degree in Biotechnology from University of Aveiro, Portugal, in 2014. During his graduation Santos was awarded with a research grant (Santander-Universities Scholarship Programme) and in the last year of the MSc studies joined to the Process and Product Applied Thermodynamics (PATh) research group, where he developed her MSc thesis within the topic "Designing new downstream processes based in FPLC and ABS methodologies”. João Santos is currently a PhD student in Chemical Engineering at the University of Aveiro, Portugal, working on the development of novel downstream processes using aqueous biphasic systems technology and in the PEGylation field for biopharmaceutical and biosensing proposes. In his PhD he is working in close colaboration with Pharmaceutical Sciencies Department at University of São Paulo (USP), conducted a 1-year period of exchange at Laboratory of Nanobiotechnology in USP. 

Publications

Building better biobetters: From fundamentals to industrial application

Torres-Obreque, KM; Meneguetti, GP; Muso-Cachumba, JJ; Feitosa, VA; Santos, JHPM; Ventura, SPM; Rangel-Yagui, CO
2022, DRUG DISCOVERY TODAY, 27, 1, 65-81.

Lysine-PEGylated Cytochrome C with Enhanced Shelf-Life Stability

Santos, JHPM; Feitosa, VA; Meneguetti, GP; Carretero, G; Coutinho, JAP; Ventura, SPM; Rangel-Yagui, CO
2022, BIOSENSORS-BASEL, 12, 2.

Purification of Pseudomonas sp. proteases through aqueous biphasic systems as an alternative source to obtain bioactive protein hydrolysates

Pillaca-Pullo, OS; Intiquilla, A; Santos, JHPM; Sanchez-Moguel, I; Brandelli, A; Zavaleta, AI
2021, BIOTECHNOLOGY PROGRESS, 37, 3.
ISBN: 1520-6033

Sustainable Strategy Based on Induced Precipitation for the Purification of Phycobiliproteins

Martins, M; Soares, BP; Santos, JHPM; Bharmoria, P; Acosta, MAT; Dias, ACRV; Coutinho, JAP; Ventura, SPM
2021, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 9, 10, 3942-3954.

Purification of green fluorescent protein using fast centrifugal partition chromatography

Soares, BP; Santos, JHPM; Martins, M; Almeida, MR; Santos, NV; Freire, MG; Santos-Ebinuma, VC; Coutinho, JAP; Pereira, JFB; Ventura, SPM
2021, SEPARATION AND PURIFICATION TECHNOLOGY, 257.
ISBN: 1873-3794

Characterization of levan produced by a Paenibacillus sp. isolated from Brazilian crude oil

Mendonca, CMN; Oliveira, RC; Freire, RKB; Piazentin, ACM; Pereira, WA; Gudina, EJ; Evtuguin, DV; Converti, A; Santos, JHPM; Nunes, C; Rodrigues, LR; Oliveira, RPS
2021, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 186, 788-799.
ISBN: 1879-0003

Controlling the l-asparaginase extraction and purification by the appropriate selection of polymer/salt-based aqueous biphasic systems

Magri, A; Pimenta, MV; Santos, JHPM; Coutinho, JAP; Ventura, SPM; Monteiro, G; Rangel-Yagui, CO; Pereira, JFB
2020, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 95, 4, 1016-1027.
ISBN: 1097-4660

Imidazolium-based Ionic Liquids as Adjuvants to Form Polyethylene Glycol with Salt Buffer Aqueous Biphasic Systems

Santos, JHPM; Martins, M; Silva, ARP; Cunha, JR; Rangel-Yagui, CO; Ventura, SPM
2020, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 65, 8, 3794-3801.
ISBN: 1520-5134

Continuous separation of cytochrome-c PEGylated conjugates by fast centrifugal partition chromatography

Santos, JHPM; Ferreira, AM; Almeida, MR; Quinteiro, PSGN; Dias, ACRV; Coutinho, JAP; Freire, MG; Rangel-Yagui, CO; Ventura, SPM
2019, GREEN CHEMISTRY, 21, 20, 5501-5506.
ISBN: 1463-9270

An integrated process combining the reaction and purification of PEGylated proteins

Santos, JHPM; Mendonca, CMN; Silva, ARP; Oliveira, RPS; Pessoa, A; Coutinho, JAP; Ventura, SPM; Rangel-Yagui, CO
2019, GREEN CHEMISTRY, 21, 23, 6407-6418.
ISBN: 1463-9270

Designing new downstream processes based in FPLC and ABS methodologies

JOÃO HENRIQUE PICADO MADALENA SANTOS
2014, supervised by Osvaldo Pessoa Jr; Sónia Patrícia Marques Ventura; .

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