abstract
Transparent corrole grafted-chitosan films were prepared by chemical modification of chitosan with a corrole macrocycle, namely, 5,10,15-tris(pentafluorophenyl)corrole (TPFC), followed by solvent casting. The obtained films were characterized in terms of absorption spectra (UV-vis), FLIM (fluorescence lifetime imaging microscopy), structure (FTIR, XPS), thermal stability (TGA), thermomechanical properties (DMA), and antibacterial activity. The results showed that the chemical grafting of chitosan with corrole units did not affect its film-forming ability and that the grafting yield increased with the reaction time. The obtained transparent films presented fluorescence which increases with the amount of grafted corrole units. Additionally, all films showed bacteriostatic effect against S. aureus, as well as good thermomechanical properties and thermal stability. Considering these features, promising applications may be envisaged for these corrole-chitosan films, such as biosensors, bioimaging agents, and bioactive optical devices.
keywords
NANOPARTICLES; PHOTOSENSITIZERS; CHEMOSENSORS; DERIVATIVES; CELLULOSE; BEHAVIOR; XPS; IR
subject category
Biochemistry & Molecular Biology; Chemistry; Polymer Science
authors
Barata, JFB; Pinto, RJB; Serra, VIRCV; Silvestre, AJD; Trindade, T; Neves, MGPMS; Cavaleiro, JAS; Daina, S; Sadocco, P; Freire, CSR
our authors
Armando Jorge Domingues Silvestre
Full professor
Carmen Sofia da Rocha Freire Barros
Coordinating Researcher
Joana Filipa Brites Barata
Post-doc Fellowship
Ricardo Pinto
Researcher
Tito Trindade
Full professoracknowledgements
The authors wish to thank to FCT (Fundacao para a Ciencia e Tecnologia) and POPH/FSE for the postdoctoral grants to J.F.B.B. (SFRH/BPD/63237/2009), R.J.B.P. (SFRH/BPD/89982/2012), and V.I.R.C.V.S. (SFRH/BPD/74270/2010). C.S.R.F. also acknowledges FCT for the research grants under the program Investigador FCT 2012 Contract No. IF/01407/2012. This work was developed within the scope of the Project CICECO-Aveiro Institute of Materials, POCI-01-0145-FEDER-007679 (FCT ref. UID/CTM/50011/2013), and QOPNA research Unit (FCT UID/QUI/00062/2013), financed by national funds through the FCT/MEC and when appropriate cofinanced by FEDER under the PT2020 Partnership Agreement and Projects REEQ/115/QUI/2005 and Pest-OE/QUI/UI0100/2013/2014.