abstract
Two dicationic water soluble mixed triamine/diamine copper (II) complexes, of general formula [Cu(dien) NN] Br-2 (1-2) [dien = diethelenetriamine and NN is en = ethylenediamine or Me4en = N, N', N, N'-tetramethylethylenediamine] were prepared under ultrasonic mode with a relatively high yield. These complexes were characterized by elemental microanalysis, UV visible IR spectroscopy, and thermal and electrochemical techniques. In addition, complex 2 structure was solved by X-ray single crystal and Hirshfeld surface analysis. The complex exhibits a distorted square pyramidal coordination environment around Cu(II) centre. The solvatochromism of the desired complexes was investigated in water and other suitable organic solvents. The results show that the Guttmann's DN parameter values of the solvents have mainly contributed to the shift of the d-d absorption band towards the linear increase in the wavelength of the absorption maxima of the complexes. The complex 1 showed higher antibacterial activity against the studied microorganisms compared to complex 2. Both complexes revealed promising antibacterial activities. (C) 2016 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.
keywords
DNA NUCLEASE ACTIVITY; DONOR LIGANDS; BIOLOGICAL-ACTIVITIES; COPPER(II) COMPLEXES; ANTICANCER ACTIVITY; BINDING; 1,10-PHENANTHROLINE; RUTHENIUM(III); CLEAVAGE; ACID
subject category
Chemistry
authors
Abu Saleemh, F; Musameh, S; Sawafta, A; Brandao, P; Tavares, CJ; Ferdov, S; Barakat, A; Al Ali, A; Al-Noaimi, M; Warad, I
our authors
Paula Cristina Ferreira da Silva Brandão
Assistant Researcheracknowledgements
The authors would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding of this Research group NO (RG-0257-1435-1436).