Current Challenges and Perspectives for the Use of Aqueous Plant Extracts in the Management of Bacterial Infections: The Case-Study of Salmonella enterica Serovars

abstract

Worldwide, foodborne diseases are a growing public health problem. Among the infectious bacteria, non-typhoidal Salmonella enterica serovars (NTS) are the major cause of hospitalization and death, and the emergence and spread of their antibiotic-resistance is becoming a worldwide health issue. This, coupled with the restrictions of antibiotics use in agriculture and animal production, calls for alternative approaches to solve this problem. Plant-derived aqueous extracts compounds could provide novel straightforward approaches to control pathogenic bacteria. This review discusses the antimicrobial activity of aqueous plant extracts against Salmonella serovars, the possible mechanisms of action involved, which components/structures might be responsible for such activity, and the current challenges for the use of these extracts/components in Salmonella infection management and their application perspectives.

keywords

VITRO ANTIMICROBIAL ACTIVITY; SIMILIPAL BIOSPHERE RESERVE; ANTIBACTERIAL ACTIVITY; IN-VITRO; MEDICINAL-PLANTS; ANTIFUNGAL ACTIVITIES; TRADITIONAL MEDICINE; STEM BARK; ANTIINFLAMMATORY ACTIVITIES; ANTIOXIDANT PROPERTIES

subject category

Biochemistry & Molecular Biology; Chemistry

authors

Santos, SAO; Martins, C; Pereira, C; Silvestre, AJD; Rocha, SM

our authors

acknowledgements

This research was funded by the project AgroForWealth: Biorefining of agricultural and forest by-products and wastes: integrated strategic for valorization of resources towards society wealth and sustainability (CENTRO-01-0145-FEDER-000001), funded by Centro2020, through FEDER and PT2020, by FCT/MCTES which financed the project CICECO-Aveiro Institute of Materials, FCT Ref. UID/CTM/50011/2019 and QOPNA research Unit (FCT UID/QUI/00062/2019).

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