authors |
Ben-Arfa, BAE; Palama, IE; Salvado, IMM; Ferreira, JMF; Pullar, RC |
nationality |
International |
journal |
CERAMICS INTERNATIONAL |
author keywords |
Bioactive glasses; Biocompatibility; Ca/P ratio; High silica content; Sol-gel derived glass; In vitro MIT tests |
keywords |
BIOACTIVE GLASS; 45S5; PHOSPHATE; RATIO; MICROSTRUCTURE; HYDROXYAPATITE; SPECTROSCOPY; DISSOLUTION; CATALYSTS; SPECTRA |
abstract |
To highlight the effect of salt precursors on the final properties, bioactivity and biocompatibility, five quaternary (Si-Ca-P-Na) glass compositions were successfully prepared through two distinct rapid sol-gel routes; one using acetate salt precursors (A) catalysed by nitric acid, and the other using nitrate salts (N) and citric acid as a catalyst. The sols dried rapidly, and stabilised at 550 & 800 degrees C to be characterised by X ray diffraction (XRD), Magic angle spinning-Nuclear magnetic resonance (Si-29 MAS-NMR) and Fourier transform infra red spectroscopy (FTIR). Upon immersion in simulated body fluid (SBF), hydroxyapatite (HAp) formation was initially enhanced by increasing Ca-content up to 40 mol%, but the formation of calcite was favoured with further increments of Ca to 45 and 48 mol%. The A-glasses exhibited lower density and lower network connectivity compared with N-glasses. The chemical surface modifications after 4 h in SBF were more evident for N-glasses in comparison to A-glasses. The biocompatibility is favoured for the samples treated at 800 degrees C and for the samples of the higher silica contents. |
publisher |
ELSEVIER SCI LTD |
issn |
0272-8842 |
isbn |
1873-3956 |
year published |
2020 |
volume |
46 |
issue |
1 |
beginning page |
1065 |
ending page |
1075 |
digital object identifier (doi) |
10.1016/j.ceramint.2019.09.073 |
web of science category |
Materials Science, Ceramics |
subject category |
Materials Science |
unique article identifier |
WOS:000498748300127
|