abstract
Leaves from Vitis vinifera L. contain potential bioactive compounds, namely: long chain aliphatic alcohols (e.g., 1-hexacosanol, 1-octacosanol and 1-triacontanol), alpha-tocopherol, beta-sitosterol, and the triterpenes beta-amyrin and lupeol. Supercritical fluid extraction (SFE) runs were measured at lab scale using: crushed and ground biomass; pure CO2 at 300 bar and 40-80 degrees C; and CO2 modified with 5 and 10 wt.% of ethanol or ethyl acetate. Total SFE yields ranged from 1.86 to 7.52 wt.%. The broken plus intact cells model (BICM), provided a good fitting of the SFE curves with 4.06 % error for total yield and 1.98-5.49 % for the individual yields of the said compounds. The BICM results revealed that the SFE is limited by intraparticle diffusion. Remarkable experimental and calculated selectivities were obtained for triterpenes (lupeol and beta-amyrin), starting with a score of 1.7 and increasing along time to 10-100. (C) 2020 Elsevier B.V. All rights reserved.
keywords
RESPONSE-SURFACE OPTIMIZATION; GRAPE SEED OIL; FLUID EXTRACTION; CARBON-DIOXIDE; VOLUMETRIC PROPERTIES; OPERATING-CONDITIONS; ALOE-VERA; SOLUBILITY; PRODUCTS; ETHANOL
subject category
Chemistry; Engineering
authors
de Melo, MMR; Carius, B; Simoes, MMQ; Portugal, I; Saraiva, J; Silva, CM
our authors
Carlos Manuel Silva
Associate Professor
Inês Portugal
Assistant Professoracknowledgements
This work was developed within the scope of the project CICECO-Aveiro Institute of Materials, UIDB/50011/2020 & UIDP/50011/2020, financed by national funds through the FCT/MEC and when appropriate co-financed by FEDER under the PT2020 Partnership Agreement. Authors want to thank the funding from Project AgroForWealth (CENTRO-01-0145-FEDER-000001), funded by Centro2020, through FEDER and PT2020.