Understanding the Formation of Deep Eutectic Solvents: Betaine as a Universal Hydrogen Bond Acceptor
authors Abranches, DO; Silva, LP; Martins, MAR; Pinho, SP; Coutinho, JAP
nationality International
journal CHEMSUSCHEM
author keywords green chemistry; natural deep eutectic solvents; non-ideality; trimethylglycine; zwitterions
keywords CHOLINE CHLORIDE; CARBOXYLIC-ACIDS; EXTRACTION; MEDIA
abstract The mechanism of formation of betaine-based deep eutectic solvents (DES) is presented for the first time. Due to its polarity unbalance, it was found that betaine displays strong negative deviations from ideality when mixed with a variety of different organic substances. These results pave the way for a comprehensive design of novel deep eutectic solvents. A connection to biologically relevant systems was made using betaine (osmolyte) and urea (protein denaturant), showing that these two compounds formed a DES, the molecular interactions of which were greatly enhanced in the presence of water.
publisher WILEY-V C H VERLAG GMBH
issn 1864-5631
isbn 1864-564X
year published 2020
volume 13
issue 18
beginning page 4916
ending page 4921
digital object identifier (doi) 10.1002/cssc.202001331
web of science category Chemistry, Multidisciplinary; Green & Sustainable Science & Technology
subject category Chemistry; Science & Technology - Other Topics
unique article identifier WOS:000560867800001
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  impact metrics
journal analysis (jcr 2019):
journal impact factor 7.962
5 year journal impact factor 7.928
category normalized journal impact factor percentile 90.878
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