In vitro bioactivity in glass-ceramic PMMA-co-EHA composites


We developed new composites that consist of poly(methylmethacrylate)-co-(ethyl-hexylacrylate) (PMMA-co-EHA) filled with a glass-ceramic (mol%) (70 SiO2 - 30 CaO). The in vitro bioactivity was assessed by determining the changes in surface morphology and composition after soaking in simulated body fluid (SBF) for periods of up to 21 days at 37degreesC. X-ray diffraction (XRD) and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy (SEM-EDS) after different soaking periods confirmed the growth of apatite-like deposits after 3 days. The deposits consisted of spherical aggregates of acicular crystallites.



subject category

Engineering; Materials Science


Ferreira, BJML; Duarte, MGGM; Gil, MH; Correia, RN; Roman, J; Vallet-Regi, M


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