resumo
Silver nanoparticles (NPs) encapsulated in amorphous silica shells are synthesized and evaluated for their antibacterial action using the Gram-negative Escherichia coli bacterium. These inorganic capsules are synthesized using a new approach that comprises the use of oil-in-water-in-oil (O/W/O) multiple emulsions to fabricate SiO2 capsules incorporating organically capped Ag NPs. This strategy is explored as a mean to promote the bioadhesion of the microorganisms to the silica rough surfaces while still keeping the system with a high surface area for the active metal. The results have shown that the hybrid capsules enable a slow release of cationic silver from the interior of the silica microsphere to the external medium probably through the pore channels in the shell. The antibacterial activity against E. coli is mainly determined by the Ag+ ion release rate, suggesting that these particulates can be employed as a robust system for prolonged used as an antimicrobial material.
palavras-chave
ESCHERICHIA-COLI; SILVER NANOPARTICLES; SILICA MICROSPHERES; GOLD NANOPARTICLES; HOLLOW SPHERE; MICROCAPSULES; RELEASE; ENCAPSULATION; PARTICLES; COLLOIDS
categoria
Chemistry; Science & Technology - Other Topics; Materials Science
autores
Sousa, FL; Almeida, A; Girao, AV; Fateixa, S; Trindade, T
nossos autores
Ana Violeta Girão
Investigador Júnior
Filipa Lourosa Sousa
Investigador Júnior
Sara Fateixa
Bolseiro de pós-Doutoramento
Tito Trindade
Professor CatedráticoGrupos
G1 - Materiais Porosos e Nanossistemas
G2 - Materiais Fotónicos, Eletrónicos e Magnéticos
G3 - Materiais Eletroquímicos, Interfaces e Revestimentos
agradecimentos
F. Sousa, A. Girao and S. Fateixa are thankful to FCT for the grants SFRH/BPD/71033/2010, SFRH/BPD/66407/2009, and SFRH/BPD/93547/2013, respectively. This research was financially supported by, FEDER through Programa Operacional Factores de Competitividade - COMPETE and national funds through FCT - Fundacao para a Ciencia e Tecnologia within CICECO project -FCOMP-01-0124-FERDER-037271 (FCT Ref. Pest-C/CTM/LA0011/2013) and Centre for Environmental and Marine Studies (project Pest-C/MAR/LA0017/2013) is also acknowledged.