Synthesis of functionalized N-doped graphene DNA hybrid material in a deep eutectic solvent

resumo

Herewith we have utilized the ability of a choline based deep eutectic solvent (DES) to dissolve DNA and disperse graphene for the synthesis of a Fe3O4 functionalized DNA N-doped graphene hybrid material. N-Doped graphene prepared from graphene oxide and melamine by solar radiation was found to envelop the Fe3O4 functionalized DNA in a sandwich fashion. Attachment of Fe3O4 nanoparticles and N-doped graphene on the DNA structure and long term preservation of the conformation of DNA in the hybrid material was established. The magnetic hybrid material thus generated does not appear to inhibit the growth of mammalian cells in vitro and thus demonstrates their non-toxic nature, which is useful for biomedical applications.

palavras-chave

OXYGEN REDUCTION; OXIDE; NANOPARTICLES; STABILITY; CELLS; PERFORMANCE; A549

categoria

Chemistry; Science & Technology - Other Topics

autores

Bhatt, J; Mondal, D; Devkar, RV; Prasad, K

nossos autores

Grupos

agradecimentos

KP thanks CSIR, New Delhi for the grant of CSIR-Young Scientist Awardees Project and overall financial support. JB and DM thank CSIR for SRF fellowships and an AcSIR for PhD registration. The analytical and centralized instrument facility division of the institute is acknowledged for overall analytical support. This is CSIR-CSMCRI communication no. 163/2015.

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