First complete NMR data and theoretical study of an antimicrobial formylated dihydrochalcone from Psidium guineense Sw

resumo

Chalcones are a widespread group of natural compounds characterized by the basic structure 1,3-diaryl-2-propen-1-one. In this study, we focused on the uncommon formylated chalcone 3'-formyl-2',4',6'-trihydroxy-5'-methyldihydrochalcone that possess interesting antimicrobial and anticancer potential. Considering the pharmacological relevance of this compound, we report its isolation and the first complete and unequivocal NMR data for this substance, corroborated by in silico theoretical study. In addition to that, its antibacterial potential was evaluated and the compound presented strong activity against Pseudomonas aeruginosa. [GRAPHICS] .

palavras-chave

CHALCONE SCAFFOLD

categoria

Chemistry, Applied; Chemistry, Medicinal

autores

Lima, EM; Fernando, LM; Felix, LP; de Oliveira, AA; Neto, ANC; Moura, RT; Teles, YCF

nossos autores

Partilhe este projeto

Publicações similares

Usamos cookies para atividades de marketing e para lhe oferecer uma melhor experiência de navegação. Ao clicar em “Aceitar Cookies” você concorda com nossa política de cookies. Leia sobre como usamos cookies clicando em "Política de Privacidade e Cookies".