authors |
Lima, EM; Fernando, LM; Felix, LP; de Oliveira, AA; Neto, ANC; Moura, RT; Teles, YCF |
nationality |
International |
journal |
NATURAL PRODUCT RESEARCH |
author keywords |
3 '-formyl-2 ',4 ',6 '-trihydroxy-5 '-methyldihydrochalcone; Psidium guineense Sw; Pseudomonas aeruginosa; DFT |
keywords |
CHALCONE SCAFFOLD |
abstract |
Chalcones are a widespread group of natural compounds characterized by the basic structure 1,3-diaryl-2-propen-1-one. In this study, we focused on the uncommon formylated chalcone 3'-formyl-2',4',6'-trihydroxy-5'-methyldihydrochalcone that possess interesting antimicrobial and anticancer potential. Considering the pharmacological relevance of this compound, we report its isolation and the first complete and unequivocal NMR data for this substance, corroborated by in silico theoretical study. In addition to that, its antibacterial potential was evaluated and the compound presented strong activity against Pseudomonas aeruginosa. [GRAPHICS] . |
publisher |
TAYLOR & FRANCIS LTD |
issn |
1478-6419 |
isbn |
1478-6427 |
year published |
2021 |
volume |
36 |
issue |
1 |
beginning page |
419 |
ending page |
423 |
digital object identifier (doi) |
10.1080/14786419.2020.1771709 |
web of science category |
5 |
subject category |
Chemistry, Applied; Chemistry, Medicinal |
unique article identifier |
WOS:000545136900001
|
ciceco authors
impact metrics
journal analysis (jcr 2019):
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journal impact factor |
2.158 |
5 year journal impact factor |
1.885 |
category normalized journal impact factor percentile |
46.029 |
dimensions (citation analysis):
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altmetrics (social interaction):
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