Plants of the Genus Terminalia: An Insight on Its Biological Potentials, Pre-Clinical and Clinical Studies

resumo

The evaluation and confirmation of healing properties of several plant species of genus Terminalia based on their traditional uses and the clinical claims are of utmost importance. Genus Terminalia has received more attention to assess and validate the therapeutic potential and clinical approval due to its immense folk medicinal and traditional applications. Various species of Terminalia genus are used in the form of herbal medicine and formulations, in treatment of diseases, including headache, fever, pneumonia, flu, geriatric, cancer, to improve memory, abdominal and back pain, cough and cold, conjunctivitis, diarrhea, heart disorder, leprosy, sexually transmitted diseases, and urinary tract disorders. These are reported to possess numerous biological properties, counting: antibacterial, antifungal, antiinflammatory, antiviral, antiretroviral, antioxidant, and antipa7rasitic. This current research review aims to update the detailed biological activities, pre-clinical and clinical studies of various extracts and secondary metabolites from several plant species under the genus Terminalia, along with information on the traditional uses and chemical composition to develop a promising strategy for their potential applications in the form of medicine or use in modern drug formulations for treating diseases like pneumonia, flu, and other types of viral infections or controlling human contagions.

palavras-chave

CANCER CELL-GROWTH; IN-VITRO; MEDICINAL-PLANTS; SILVER NANOPARTICLES; GOLD NANOPARTICLES; GALLIC ACID; ARJUNA BARK; ANTIMICROBIAL ACTIVITY; SUBACUTE TOXICITY; EXTRACTS INHIBIT

categoria

Pharmacology & Pharmacy

autores

Das, G; Kim, D; Fan, C; Gutierrez-Grijalva, EP; Heredia, JB; Nissapatorn, V; Mitsuwan, W; Pereira, ML; Nawaz, M; Siyadatpanah, A; Norouzi, R; Sawicka, B; Shin, HS; Patra, JK

Grupos

agradecimentos

This work was supported by Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry (IPET) through Innovative Food Product and Natural Food Materials Development Program (No. 319049-3), funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA).

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