resumo
This work is a proof of concept for making load bearing implants with osseointegration and bone bonding ability. Yttria-stabilized zirconia (YSZ) scaffolds with a percentage of macro porosity of about 70% were fabricated by robocasting. Although a maximum solids volume fraction of 50 vol.% could be achieved, the 3D-printing process revealed to be more reliable when using inks with 48 vol.% solids. The sintered porous structures exhibited an average compressive strength of similar to 236 MPa. After some preliminary coating experiments, an ethanol slurry of fine bioactive glass (BG) particles (10 wt.%) stabilized with polyvinylpyrrolidone was used to deposit a uniform surface coating onto the filaments, followed by glazing at 850 degrees C. The functionalized scaffolds showed a relatively uniform surface coverage by the bioactive glass. The results of in vitro testing by immersing the scaffolds in simulated body fluid (SBF) showed remarkable morphological surface changes and an extensive deposition of hydroxyapatite layer. The overall results demonstrate the viability of producing porous YSZ scaffolds with excellent bioactivity, which are promising for bone tissue engineering under load bearing applications.
palavras-chave
ZIRCONIA-TOUGHENED ALUMINA; FINITE-ELEMENT-ANALYSIS; BONE; HYDROXYAPATITE; COATINGS; CERAMICS; SUBSTITUTES; COMPOSITES; PLASMA; REPAIR
categoria
Materials Science
autores
Gaddam, A; Brazete, DS; Neto, AS; Nan, B; Fernandes, HR; Ferreira, JMF
nossos autores
Ana Sofia Neto
Estudante de doutoramentoAnuraag Gaddam
Investigador Auxiliar
Bo Nan
Bolseiro de investigação
Hugo Alexandre Gonçalves da Rocha Fernandes
Investigador Júnior
José Maria da Fonte Ferreira
Professor(a) Jubilado(a)
Nan Bo
Estudante de doutoramentoGrupos
G1 - Materiais Porosos e Nanossistemas
G3 - Materiais Eletroquímicos, Interfaces e Revestimentos
G5 - Materiais Biomiméticos, Biológicos e Vivos
agradecimentos
Centro de Investigacao em Materiais Ceramicos e Compositos, Grant/Award Number: UID/CTM/50011/2019