abstract
This work is a proof of concept for making load bearing implants with osseointegration and bone bonding ability. Yttria-stabilized zirconia (YSZ) scaffolds with a percentage of macro porosity of about 70% were fabricated by robocasting. Although a maximum solids volume fraction of 50 vol.% could be achieved, the 3D-printing process revealed to be more reliable when using inks with 48 vol.% solids. The sintered porous structures exhibited an average compressive strength of similar to 236 MPa. After some preliminary coating experiments, an ethanol slurry of fine bioactive glass (BG) particles (10 wt.%) stabilized with polyvinylpyrrolidone was used to deposit a uniform surface coating onto the filaments, followed by glazing at 850 degrees C. The functionalized scaffolds showed a relatively uniform surface coverage by the bioactive glass. The results of in vitro testing by immersing the scaffolds in simulated body fluid (SBF) showed remarkable morphological surface changes and an extensive deposition of hydroxyapatite layer. The overall results demonstrate the viability of producing porous YSZ scaffolds with excellent bioactivity, which are promising for bone tissue engineering under load bearing applications.
keywords
ZIRCONIA-TOUGHENED ALUMINA; FINITE-ELEMENT-ANALYSIS; BONE; HYDROXYAPATITE; COATINGS; CERAMICS; SUBSTITUTES; COMPOSITES; PLASMA; REPAIR
subject category
Materials Science
authors
Gaddam, A; Brazete, DS; Neto, AS; Nan, B; Fernandes, HR; Ferreira, JMF
our authors
Ana Sofia Neto
PhD StudentAnuraag Gaddam
Assistant Researcher
Bo Nan
Research Fellowship
Hugo Alexandre Gonçalves da Rocha Fernandes
Junior Researcher
José Maria da Fonte Ferreira
Retired Professor
Nan Bo
PhD StudentGroups
G1 - Porous Materials and Nanosystems
G3 - Electrochemical Materials, Interfaces and Coatings
G5 - Biomimetic, Biological and Living Materials
acknowledgements
Centro de Investigacao em Materiais Ceramicos e Compositos, Grant/Award Number: UID/CTM/50011/2019