Supervisões em Curso
Projectos
Exploração do Potencial Regenerativo e Translacional de Fibras Celulares (CellFi)
CoordenadorFundação para a Ciência e a Tecnologia
Células mesenquimais estaminais Estruturas sem scaffold Fibras Celulares RegeneraçãoExploring devitalized MSCs fibres as immunomodulatory devices for wound regeneration through (i) direct promotion of healing or (ii) enabling of allograft transplantation free of systemic immunosuppression (LAZARUS)
CoordenadorOther International
The project aims at exploring MSCs as constituents of off-the-shelf easy-to-handle immunomodulatory biomaterials. The project focuses on using these materials to treat difficult-to-heal wounds, which may be chronic, or have proneness to become chronic if not properly treated.Two treatment approaches will be explored using devitalized MSC aggrega...Ativação metabólica da diferenciação 3D de células estaminais em tecido ósseo (BetterBone)
ParticipanteFundação para a Ciência e a Tecnologia
Estratégias que envolvam a diferenciação osteogénica de células estaminais mesenquimais (MSCs) representam ferramentas promissoras na medicina regenerativa, tanto através da promoção da regeneração in situ, como da implanta&...Bioengenharia de dispositivos híbridos hierárquicos com capacidade de auto oxigenação (O2CELLS)
ParticipanteFundação para a Ciência e a Tecnologia
A engenharia de tecidos surgiu como uma solução alternativa para fornecer suportes estruturais temporários no local do defeito até que o tecido nativo seja regenerado endogenamente e a função normal seja restaurada. Apesar dos progressos realizados nos últimos 20 anos, ainda não é possível abordar toda a complexidade e propriedades multifunciona...Bioreactor para Engenharia de Tecido Osseo Conduzido por Metabolomica (BioImplant)
ParticipanteFundação para a Ciência e a Tecnologia
Cápsulas esféricas multicompartimentalizadas de alto rendimento para a transplantação de co-culturas multimodais de células estaminais derivadas do tecido adiposo e ilhotas pancreáticas. (TranSphera)
ParticipanteFundação para a Ciência e a Tecnologia
Desenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
ParticipanteFundação para a Ciência e a Tecnologia
Development and testing of multifunctional carriers based on micro- and nanoscale engineering for targeted, controlled, and safe delivery of agrochemicals to crops. PTDC/BAA- Curriculum Vitae – Mariana Braga de Oliveira 11 of 19 AGR/29258/2017 (Agritarget)
ParticipanteFundação para a Ciência e a Tecnologia
Innovative tools to treat and model complex cancer environments (TheraTools)
ParticipanteEuropean Comission
Funded by the Marie Skłodowska-Curie Actions programme, the TheraTools project will create a multidisciplinary research and training network to focus on the technological development of scientific tools to study malignant tumours localised beyond a biological barrier, as in the case of brain tumours. The TheraTools consortium will provide high-q...Merging Sustainable and Digital Chemical Technologies for The Development of Greener-Bydesign Pharmaceuticals (SusPharma)
ParticipanteEuropean Comission
Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern ...Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
ParticipanteFundação para a Ciência e a Tecnologia
Publicações
Controlling the diffusion of small molecules from matrices processed by all-aqueous methodologies: towards the development of green pharmaceutical products
Bárbara S. Neves, Raquel C. Gonçalves, João F. Mano, Mariana B. Oliveira
2024, Green Chemistry.
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Natural polymer‐polyphenol bioadhesive coacervate with stable wet adhesion, antibacterial activity, and on‐demand detachment
Margarida MA Sacramento, Mariana B Oliveira, José RB Gomes, João Borges, Benjamin R Freedman, David J Mooney, João MM Rodrigues, João F Mano
2024, Advanced Healthcare Materials, 13.
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Encapsulated Mesenchymal Stromal Cells as Cyclic Providers of Immunomodulatory Secretomes: a living on‐Demand Delivery System
Ana Rita Sousa, Diana C Gonçalves, Beatriz Guapo Neves, Ana Santos‐Coquillat, Mariana B Oliveira, João F Mano
2024, Advanced Healthcare Materials.
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Shape‐Versatile Fixed Cellular Materials for Multiple Target Immunomodulation
Ana Rita Sousa, Ana Filipa Cunha, Ana Santos‐Coquillat, Beatriz Hernaez Estrada, Kara Spiller, Marta Barão, Artur Filipe Rodrigues, Susana Simões, Andreia Vilaça, Lino Ferreira, Mariana B Oliveira, João F Mano
2024, Advanced Materials.
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Reversible imine crosslinking in waterborne self-healing polymer coatings
Martins, TD; Viciosa, MT; Oliveira, MB; Fernandes, A; Mano, JF; Baleiza, C; Farina, JPS
2023, PROGRESS IN ORGANIC COATINGS, 180.
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Advanced hydrogels based on natural macromolecules: chemical routes to achieve mechanical versatility
Mortier, C; Costa, DCS; Oliveira, MB; Haugen, HJ; Lyngstadaas, SP; Blaker, JJ; Mano, JF
2022, MATERIALS TODAY CHEMISTRY, 26.
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AIR-FOAMED HYDROGELS FOR HOMOGENOUS CELL VIABILITY IN LARGE CONSTRUCTS
Salvador, T; Oliveira, MB; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S401-S401.
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All-Aqueous Freeform Fabrication of Perfusable Self-Standing Soft Compartments
Goncalves, RC; Vilabril, S; Neves, CMSS; Freire, MG; Coutinho, JAP; Oliveira, MB; Mano, JF
2022, ADVANCED MATERIALS, 34, 31.
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An Intracellular Metabolic Signature as a Potential Donor-Independent Marker of the Osteogenic Differentiation of Adipose Tissue Mesenchymal Stem Cells
Bispo, DSC; Jesus, CSH; Romek, K; Marques, IMC; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 23.
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Cell Response in Free-Packed Granular Systems
Cunha, AF; Matias, AFV; Dias, CS; Oliveira, MB; Araujo, NAM; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 36, 40469-40480.
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