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Equipa
Mara Guadalupe Freire Martins
Investigador CoordenadorDescrição
Immunoglobulins (or antibodies) are molecules produced by our white blood cells; the immunoglobins recognise 'invaders' and aid in their destruction. Humans make five different classes, one of which is similar in function to IgY, an unusual antibody made by chickens. The circulating IgY accumulates in the yolk of chicken eggs. This is convenient because scientists can immunise chickens against a variety of pathogens, including those that infect humans, and then purify the IgY antibodies from egg yolk, without tackling the complex production of human-derived monoclonal antibodies. Now, the EU-funded PureIgY project is developing a simpler and less expensive method to isolate IgY that will also enhance yield significantly. The team is focused on utilising the innovative platform to speedily develop therapies for antimicrobial-resistant pathogens.
Coordenador
Coordenação
Universidade de Aveiro (UA)
Participantes
Não
Resultados
Purification of immunoglobulin Y from egg yolk using thermoresponsive aqueous micellar two-phase systems comprising ionic liquids
Vicente, FA; Castro, LS; Mondal, D; Coutinho, JAP; Tavares, APM; Ventura, SPM; Freire, MGAdvances Achieved by Ionic-Liquid-Based Materials as Alternative Supports and Purification Platforms for Proteins and Enzymes
Bento, RMF; Almeida, CAS; Neves, MC; Tavares, APM; Freire, MGFinanciadores
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