Towards the use of IgY antibodies as alternative therapeutics
tipo de financiamento European Comission
programa ERC-2019-POC - ERC Proof of Concept Grant
referência alternative 899921
grupo(s) de investigação 5 - materiais biomédicos e biomiméticos;
departamento Chemistry (DQ)
período de execução 2020-06-01 - 2021-11-30 ( 18 Meses )
Immunoglobulins (or antibodies) are molecules produced by our white blood cells; the immunoglobins recognise 'invaders' and aid in their destruction. Humans make five different classes, one of which is similar in function to IgY, an unusual antibody made by chickens. The circulating IgY accumulates in the yolk of chicken eggs. This is convenient because scientists can immunise chickens against a variety of pathogens, including those that infect humans, and then purify the IgY antibodies from egg yolk, without tackling the complex production of human-derived monoclonal antibodies. Now, the EU-funded PureIgY project is developing a simpler and less expensive method to isolate IgY that will also enhance yield significantly. The team is focused on utilising the innovative platform to speedily develop therapies for antimicrobial-resistant pathogens.
/ip local
Mara Guadalupe Freire Martins
ciceco status Coordenador
instituíção proponente Universidade de Aveiro (UA)
instituições participante(s) no
participação industrial Não
parceiro(s) internacional Não
orçamento total 150.000€
orçamento ciceco 150.000€
centro de custos 3.89.317