Towards the use of IgY antibodies as alternative therapeutics
funding type European Comission
programme ERC-2019-POC - ERC Proof of Concept Grant
alternative reference 899921
research group(s) 5 - biomedical and biomimetic materials;
department Chemistry (DQ)
execution dates 2020-06-01 - 2021-11-30 ( 18 Months )
Immunoglobulins (or antibodies) are molecules produced by our white blood cells; the immunoglobins recognise 'invaders' and aid in their destruction. Humans make five different classes, one of which is similar in function to IgY, an unusual antibody made by chickens. The circulating IgY accumulates in the yolk of chicken eggs. This is convenient because scientists can immunise chickens against a variety of pathogens, including those that infect humans, and then purify the IgY antibodies from egg yolk, without tackling the complex production of human-derived monoclonal antibodies. Now, the EU-funded PureIgY project is developing a simpler and less expensive method to isolate IgY that will also enhance yield significantly. The team is focused on utilising the innovative platform to speedily develop therapies for antimicrobial-resistant pathogens.
/local pi
Mara Guadalupe Freire Martins
ciceco status Coordinator
proponent institution Universidade de Aveiro (UA)
partner institution(s) no
industrial partner(s) no
international partner(s) no
total budget 150.000€
ciceco budget 150.000€
project code 3.89.317