TISSUE REACTOR - Development of a Bioreactor-Based Connective Tissue Production Line
tipo de financiamento European Comission
programa FP5-GROWTH
acrónimo/
referência
TISSUE REACTOR
referência alternative G5RD-CT-2000-00282
grupo(s) de investigação 5 - materiais biomédicos e biomiméticos;
departamento Materials and Ceramic Engineering (DEMaC)
período de execução 2001-02-01 - 2004-01-31 ( 36 Meses )
data de extensão projeto 2005-02-01 ( 12 Meses extra )
resumo/
palavras-chave
It is the aim of this project to engineer connective tissue in vitro and to demonstrate its applicability as a tissue substitute in vivo. To achieve this goal a continuous cultivation process based on a perfused fixed-bed bioreactor system and its components will be developed which allows the production of large quantities of three-dimensional (3-d) tissue cultures in combination with capillary-like prevascular precursors to form in vitro tissue constructs. The primary focus will be bone tissue, and bone tissue constructs will then subsequently be implanted in vivo to demonstrate their potential to improve current limitations in bone substitution surgery.
coordenador
/ip local
Maria Margarida Tavares Lopes Almeida
ciceco status Parceiro
instituíção proponente University of Ulm<br />Germany
instituições participante(s) BIOSCAN B.V.; Netherlands; CAM IMPLANTS B.V.; Netherlands; GBF - NATIONAL CENTRE FOR BIOTECHNOLOGY; Germany; MEREDOS GMBH; Germany; MNEMOSCIENCE GMBH; Germany; UNIVERSITY OF AVEIRO; Portugal; UNIVERSITY OF MANCHESTER; United Kingdom; UNIVERSITY OF NOTTINGHAM; United Kingdom;
participação industrial Sim
parceiro(s) internacional Sim
orçamento total 2.881.000€
orçamento ciceco 233.600€
centro de custos 3.50.62
link http://cordis.europa.eu/project/rcn/54250_en.html
publicações
Apoio

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