TISSUE REACTOR - Development of a Bioreactor-Based Connective Tissue Production Line
| funding type | European Comission |
| programme | FP5-GROWTH |
|
acronym/ reference |
TISSUE REACTOR |
| alternative reference | G5RD-CT-2000-00282 |
| research group(s) |
5 - biomedical and biomimetic materials; |
| department | Materials and Ceramic Engineering (DEMaC) |
| execution dates | 2001-02-01 - 2004-01-31 ( 36 Months ) |
| project extension date | 2005-02-01 ( 12 Extra months ) |
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abstract/ keywords |
It is the aim of this project to engineer connective tissue in vitro and to demonstrate its applicability as a tissue substitute in vivo. To achieve this goal a continuous cultivation process based on a perfused fixed-bed bioreactor system and its components will be developed which allows the production of large quantities of three-dimensional (3-d) tissue cultures in combination with capillary-like prevascular precursors to form in vitro tissue constructs. The primary focus will be bone tissue, and bone tissue constructs will then subsequently be implanted in vivo to demonstrate their potential to improve current limitations in bone substitution surgery. |
|
coordinator /local pi |
Maria Margarida Tavares Lopes Almeida |
| ciceco status | Partner |
| proponent institution | University of Ulm<br />Germany |
| partner institution(s) | BIOSCAN B.V.; Netherlands; CAM IMPLANTS B.V.; Netherlands; GBF - NATIONAL CENTRE FOR BIOTECHNOLOGY; Germany; MEREDOS GMBH; Germany; MNEMOSCIENCE GMBH; Germany; UNIVERSITY OF AVEIRO; Portugal; UNIVERSITY OF MANCHESTER; United Kingdom; UNIVERSITY OF NOTTINGHAM; United Kingdom; |
| industrial partner(s) | yes |
| international partner(s) | yes |
| total budget | 2.881.000€ |
| ciceco budget | 233.600€ |
| project code | 3.50.62 |
| link | http://cordis.europa.eu/project/rcn/54250_en.html |
project members
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