abstract
The aim of the present study was to prepare resorbable hydroxyapatite (HA) based bone graft materials reinforced with carbon nanotubes as a way to cope with the inability of pure HA to resorb and its intrinsic brittleness and poor strength that restrict its clinical applications under load-bearing conditions. With this purpose, a Si-doped HA nanopowder (n-Si(0.8)HA) was prepared by chemical synthesis and used as composite matrix reinforced with different amounts of functionalized multiwall carbon nanotubes (MWCNTs). The effect of the added amounts of MWCNTs on the mechanical properties of nanocomposites and their in vitro biomineralization was assessed by bending strength measurements, immersing tests in simulated body fluid solution (SBF), scanning electron microscopy (SEM), and inductively coupled plasma atomic emission spectroscopy analysis (ICP-AES). The bioactivity and bending strength were enhanced, reaching maximum balanced values for an optimum addition of 3 wt.% f-MWCNTs. These results might contribute to broaden the potential applications of HA-based bone grafts.
keywords
SILICON-SUBSTITUTED HYDROXYAPATITE; SIMULATED BODY-FLUID; BIOMEDICAL APPLICATIONS; IN-VITRO; BEHAVIOR; COMPOSITES; DEPOSITION; CA-10(PO4)(6-X)(SIO4)(X)(OH)(2-X); OSTEOBLASTS; GRANULES
subject category
Chemistry; Science & Technology - Other Topics; Materials Science; Physics
authors
Belmamouni, Y; Bricha, M; Essassi, E; Ferreira, JMF; El Mabrouk, K
our authors
José Maria da Fonte Ferreira
Retired Professoracknowledgements
The project was sponsored by MASCIR Moroccan for Advanced Science, Research and Innovation Foundation. The support from CICECO is also greatly appreciated.