Sol-gel preparation and in vitro test of fluorapatite/hydroxyapatite films


Fluorapatite/hydroxyapatite (FA/HA) films have been demonstrated to be a good alternative to pure hydroxyapatite (HA) ones in medical applications because of their bioactivity and relatively low solubility. In this study, Ca(NO3)(2), P2O5, and HPF6 were used to prepare FA/HA films on Ti6Al4V substrate with the use of a sol-gel method. The F contents in the films could be tailored by adjusting the amount of HPF6 added. The in vitro evaluation of the films was carried out in both SBF9# solution and TRIS buffer solution. The films with appropriate F contents showed a better ability to induce calcium phosphate deposition on their surfaces than either pure HA film and FA/HA films with even higher F content, as well as smaller dissolution amounts than HA film in TRIS buffer solution. Hence, the FA/HA films obtained in this work integrate both good bioactivity and stability, and could be a better choice for bioactive film on titanium alloys to produce high-quality implants. (C) 2003 Wiley Periodicals, Inc.



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Engineering; Materials Science


Cheng, K; Weng, WJ; Qu, HB; Du, PY; Shen, G; Han, GR; Yang, J; Ferreira, JMF

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