Influence of albumin on mineralization of PMMA-based/glass composites
authors Ferreira, BJML; Duarte, MGGM; Gil, MH; Fernandes, MHV; Correia, RN
nationality International
journal JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS
author keywords Biomineralization; Bovine serum albumin; PMMA based materials; PMMA-co-EHA; PMMA-based/glass composites
keywords BOVINE SERUM-ALBUMIN; IN-VITRO BIOACTIVITY; CO-EHA COMPOSITES; CONFORMATIONAL-CHANGES; PROTEIN ADSORPTION; GEL GLASSES; SURFACE; HYDROXYAPATITE; BONE; CERAMICS
abstract Purpose: The formation of a calcium phosphate layer on the surface of bone tissue engineering biomaterials is crucial for their integration in bone. Simulated biological fluids used to study the in vitro formation of those layers do not usually contain important organic components present in vivo. notably proteins. In this work the influence of bovine serum albumin on the mineralization process of poly(methylmethacrylate)-based composite was studied in vitro. Methods: The effect of protein on calcium phosphate formation was followed by ion concentration analyses (ICP), x-ray diffraction (XRD), and scanning electron microscopy coupled with x-ray energy dispersive spectroscopy (SEM-EDS). Results and Conclusions: The results showed the precipitation of a calcium phosphate layer on the surface of composites immersed in SBF and SBFA. Further transformation and crystallization of this layer, initially amorphous, appears to be influenced by the presence of albumin.
publisher WICHTIG EDITORE
issn 2280-8000
year published 2012
volume 10
issue 2
beginning page 92
ending page 98
digital object identifier (doi) 10.5301/JABFM.2012.9254
web of science category Biophysics; Engineering, Biomedical; Materials Science, Biomaterials
subject category Biophysics; Engineering; Materials Science
unique article identifier WOS:000309588000003
  ciceco authors
  impact metrics
journal analysis (jcr 2019):
journal impact factor 2
5 year journal impact factor 1.679
category normalized journal impact factor percentile 29.409
dimensions (citation analysis):
altmetrics (social interaction):



 


Apoio

1suponsers_list_ciceco.jpg