Maria Clara Gomes

Assistant Researcher

Ongoing Supervisions

Projects

Development of a multifunctional biomaterial patch for buccal delivery of peptide-analogue treatments (BUCCAL-PEP)

PartnerEuropean Comission
Oral delivery of peptide macromolecules represents significant challenges for pharmaceutical research, including low bioavailability, dosage control and undesirable food interactions. The intention of the EU-funded BUCCAL-PEP project is to develop a technological platform for oromucosal delivery suitable for a broad range of peptide-ana...

High-tech sustainable biofabrication for advancing personalized healthcare (LEGO)

PartnerFundação para a Ciência e a Tecnologia
This research proposal aims to engineer and validate, for the first time, a simple, sustainable, and highly translational methodology for obtaining extracellular matrix-rich tissue-specific bioinks. Patient's own cells will be the main building blocks for the development of realistic microtissues, which will be used to engineer a h...

Metastasis Exploration in the Bone Microenvironment - Breast Cancer Edition (METABONE)

CoordinatorFundação para a Ciência e a Tecnologia

PRInted Symbiotic Materials as a dynamic platform for Living Tissues production (PRISM-LT)

PartnerEuropean Comission
The EU-funded PRISM-LT project will use a hybrid living materials concept to create a flexible platform for living tissue manufacturing. The innovative bio-ink will contain stem cells integrated into a supporting matrix with engineered helper bacteria or yeast cells. The bioprinting process will produce a 3D patterned structure where stem cells ...

Publications

Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies

Martins, EAG; Deus, IA; Gomes, MC; Silva, AS; Mano, JF; Custódio, CA
2025, ADVANCED HEALTHCARE MATERIALS, 14, 1.
ISBN: 2192-2659

Bioactive Self-Regulated Liquified Microcompartments to Bioengineer Bone-Like Microtissues

Pinho, AR; Gomes, MC; Costa, DCS; Mano, JF
2024, SMALL, 20, 9.
ISBN: 1613-6829

Human Platelet Lysate-Derived Nanofibrils as Building Blocks to Produce Free-Standing Membranes for Cell Self-Aggregation

Monteiro, C; Gomes, MC; Bharmoria, P; Freire, MG; Coutinho, JAP; Custódio, CA; Mano, JF
2024, ACS NANO, 18, 24, 15815-15830.
ISBN: 1936-086X

Designing of a Multifunctional 3D-Printed Biomimetic Theragenerative Aerogel Scaffold via Mussel-Inspired Chemistry: Bioactive Glass Nanofiber-Incorporated Self-Assembled Silk Fibroin with Antibacterial, Antiosteosarcoma, and Osteoinductive Properties

Abie, N; Ünlü, C; Pinho, AR; Gomes, MC; Remmler, T; Herb, M; Grumme, D; Tabesh, E; Shahbazi, MA; Mathur, S; Mano, JF; Maleki, H
2024, ACS APPLIED MATERIALS & INTERFACES, 16, 18, 22809-22827.
ISBN: 1944-8252

A Self-Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture

Zargarzadeh, M; Gomes, MC; Patrício, SG; Custódio, CA; Mano, JF
2023, ADVANCED FUNCTIONAL MATERIALS, 33, 48.

Self-Assembly of Platelet Lysates Proteins into Microparticles by Unnatural Disulfide Bonds for Bottom-Up Tissue Engineering

Gomes, MC; Pinho, AR; Custódio, C; Mano, JF
2023, ADVANCED MATERIALS, 35, 41.

Emerging modulators for osteogenic differentiation: a combination of chemical and topographical cues for bone microenvironment engineering

Jesus, D; Pinho, AR; Gomes, MC; Oliveira, CS; Mano, JF
2022, SOFT MATTER, 18, 16, 3107-3119.

Fabrication of Antibacterial, Osteo-Inductor 3D Printed Aerogel-Based Scaffolds by Incorporation of Drug Laden Hollow Mesoporous Silica Microparticles into the Self-Assembled Silk Fibroin Biopolymer

Ng, P; Pinho, AR; Gomes, MC; Demidov, Y; Krakor, E; Grume, D; Herb, M; Le, K; Mano, J; Mathur, S; Maleki, H
2022, MACROMOLECULAR BIOSCIENCE, 22, 4.

High-Throughput Production of Microsponges from Platelet Lysate for Tissue Engineering Applications

Ladeira, BMF; Gomes, MC; Custodio, CA; Mano, JF
2022, TISSUE ENGINEERING PART C-METHODS, 28, 7, 325-334.

Universal Strategy for Designing ShapeMemory Hydrogels

Costa, DCS; Costa, PDC; Gomes, MC; Chandrakar, A; Wieringa, PA; Moroni, L; Mano, JF
2022, ACS MATERIALS LETTERS, 4, 4, 701-706.

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