News

  1. Home
  2. About
6 June 2023

Unveiled New Promising Advances in Magnetic Hyperthermia for Oncologic Treatments

Unveiled New Promising Advances in Magnetic Hyperthermia for Oncologic Treatments

A team of researchers from CICECO and the Department of Physics of the University of Aveiro, in collaboration with researchers from INMA at the University of Zaragoza, in Spain, published a study in the prestigious journal ACS Nano, pointing out a promising technique for real-time temperature mapping during the application of an external magnetic field such as in magnetic hyperthermia, a technique used in the treatment of oncological diseases.

Magnetic hyperthermia is a technique used in cancer treatments, but the low heating power of magnetic nanoparticles available for use in humans is a limitation that restricts the effectiveness of the technique. The researched alternative was local intracellular hyperthermia, which uses small amounts of heat generated at thermosensitive intracellular sites to induce cell death in a controlled manner.

"In this study we used luminescent molecular thermometers to measure the local temperature variation in magnetic nanoparticles in real time during exposure to an external magnetic field inside living cells," says Luis Carlos, corresponding author of the publication. Researcher Carlos Brites also emphasizes that "the results indicated that the nanoparticles achieved a temperature increase of up to 8°C without significantly heating the cell membrane, which may open up the possibility of developing less evasive and more efficient treatments, with a consequent decrease in side effects for patients."

The results are promising for the advancement of local intracellular hyperthermia as an effective diagnostic and therapeutic technique, especially for oncological diseases. However, further studies will be needed to evaluate the effectiveness of the technique on different types of tumors in animal models and later in humans.

The work took place in the scope of the NanoTBTech project project, financed by European funds (grant agreement 801305) and led by the University of Aveiro.

The publication is available at: https://doi.org/10.1021/acsnano.3c00388

Share this Article:

Related Articles

Researchers

Groups

G2 - Photonic, Electronic and Magnetic Materials

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".


Privacy and Cookie Policy

Personal data

CICECO-Aveiro Institute of Materials respects your privacy, ensuring confidentiality of personal data you share with the institution through this way, not collecting any personal information about you without your consent, under the terms required by General Data Protection Regulations (RGPD).

The data collected in forms are intended exclusively for processing user requests and will not be used for any other purpose, always safeguarding their confidentiality, under the terms of the protection conferred by the aforementioned regulation.

The collection and processing of data is the responsibility of CICECO and its storage is properly protected, only authorized CICECO employees can access the information within the scope of their functions, always being clear in the respective collection forms the purposes for which they are intended. The remaining issues to be considered in this matter will be handled by the University of Aveiro in accordance with the regime established by the GDPR.

Cookies policy

Cookies are small files with alphanumeric information that are stored on your computer's hard drive by your browser and are intended to improve the user experience and enhance website navigation.

Collection and use of technical information

The cookies used on CICECO are anonymous, and no information about our users that allows their personal identification is stored in them.

The technical information recorded consists of:

  • iP (Internet Protocol) address of the visitor;
  • the type of internet browser used by the website visitor and the respective operating system used;
  • the date and time of the consultation;
  • the pages visited on the site and the documents downloaded
  • The technical information collected is used for statistical purposes only.

Cookies used

Session cookies

These cookies are used to record user preferences, such as the language in which websites are displayed or to maintain authenticated user sessions, and are automatically deleted when the browser is closed.

Persistent cookies

These cookies store information that is needed between sessions. For example, a persistent cookie is set to record that you have been made aware of the cookie policy so that the message regarding this policy is not shown again the next time you visit the website. This cookie remains on the computer until it reaches its expiry date or is deleted by the user.

Data protection

The present privacy policy covers the Information System of the University of Aveiro (SIUA), governed by the General Data Protection Regulations (RGPD) Regulation (EU) No. 2016/679, of April 27th, 2016.

Data Protection Officer

The University of Aveiro has a Data Protection Officer (DPO), who ensures compliance of the processing of personal data with the legislation in force, and is available through the following email address epd@ua.pt.

Close