Tânia E. Sintra got her MSc degree in Pharmaceutical Sciences at University of Coimbra in 2011. By the middle of 2017 she completed her PhD in Chemistry by University of Aveiro, having during her PhD studies trainee at Faculty of Engineering of the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany. Since then, she is a post-doctoral researcher at CICECO-Aveiro Institute of Materials, University of Aveiro, under the scope of the R&D project SusPhotoSolutions. In 2018, she was awarder with a R&D project (Chiral resolution of drugs in centrifugal partition chromatography using enantioselective aqueous biphasic systems, ChiResus), from the Portuguese Foundation for Science and Technology (FCT), where she is the Principal Investigator (PI). Her last 6 years were dedicated to research on Chemistry and Pharmaceutical areas with focus on organic and analytical chemistry. During her scientific path she have contributed to the development of innovative research in the synthesis of benign ionic liquids to respond to major challenges of pharmaceutical industry, namely the separation of two enantiomers and the lack of aqueous solubility of some promising drugs. Since 2012, Tânia E. Sintra published 21 articles in international peer reviewed scientific journals, with more than 370 citation and an h-index of 10 (data obtained from Scopus at 17th February 2019), and presented several oral and poster communications in national and international conferences.
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2013 - 2017 | PhD in Chemistry | University of Aveiro,Thesis title "Synthesis of more benign ionic liquids for specific applications", supervised by Prof. Dr. João A.P. Coutinho (UA) and co-supervised by Prof. Dr. Sónia P.M. Ventura (UA).
2006 - 2011 | PharmD in Pharmaceutical Sciences | University of Coimbra
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Propranolol resolution using enantioselective biphasic systemsCarreira, ARF; Ferreira, AM; Almeida, MR; Coutinho, JAP; Sintra, TE 2021, SEPARATION AND PURIFICATION TECHNOLOGY, 254,
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Cholinium-based ionic liquids as bioinspired hydrotropes to tackle solubility challenges in drug formulationSintra, TE; Abranches, DO; Benfica, J; Soares, BP; Ventura, SPM; Coutinho, JAP 2021, EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 164, 86-92.
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The impact of the counterion in the performance of ionic hydrotropesAbranches, DO; Benfica, J; Soares, BP; Ferreira, AM; Sintra, TE; Shimizu, S; Coutinho, JAP 2021, CHEMICAL COMMUNICATIONS, 57, 23, 2951-2954.
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Study of the partition of sodium diclofenac and norfloxacin in aqueous two-phase systems based on copolymers and dextranAhsaie, FG; Pazuki, G; Sintra, TE; Carvalho, P; Ventura, SPM 2021, FLUID PHASE EQUILIBRIA, 530,
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Sequential recovery of C-phycocyanin and chlorophylls from Anabaena cylindricaSintra, TE; Bagagem, SS; Ahsaie, FG; Fernandes, A; Martins, M; Macario, IPE; Pereira, JL; Goncalves, FJM; Pazuki, G; Coutinho, JAP; Ventura, SPM 2021, SEPARATION AND PURIFICATION TECHNOLOGY, 255,
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Enhancing Artemisinin Solubility in Aqueous Solutions: Searching for Hydrotropes based on Ionic LiquidsSales, I; Abranches, DO; Costa, P; Sintra, TE; Ventura, SPM; Mattedi, S; Coutinho, JAP; Freire, MG; Pinho, SP 2021, FLUID PHASE EQUILIBRIA, 534,
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Solubility of H2S in ammonium-based ionic liquidsSousa, JMMV; Sintra, TE; Ferreira, AGM; Carvalho, PJ; Fonseca, IMA 2021, JOURNAL OF CHEMICAL THERMODYNAMICS, 154,
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Encapsulated Amino-Acid-Based Ionic Liquids for CO(2)CaptureSilva, LP; Moya, C; Sousa, M; Santiago, R; Sintra, TE; Carreira, ARF; Palomar, J; Coutinho, JAP; Carvalho, PJ 2020, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2020, 33, 3158-3166.
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Glycerol Ethers as Hydrotropes and Their Use to Enhance the Solubility of Phenolic Acids in WaterSoares, BP; Abranches, DO; Sintra, TE; Leal-Duaso, A; Garcia, JI; Pires, E; Shimizu, S; Pinho, SP; Coutinho, JAP 2020, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 8, 14, 5742-5749.
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Unveiling the mechanism of hydrotropy: evidence for water-mediated aggregation of hydrotropes around the soluteAbranches, DO; Benfica, J; Soares, BP; Leal-Duaso, A; Sintra, TE; Pires, E; Pinho, SP; Shimizu, S; Coutinho, JAP 2020, CHEMICAL COMMUNICATIONS, 56, 52, 7143-7146.
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Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded with phenolic-based ionic liquids for cutaneous applicationMorais, ES; Silva, NHCS; Sintra, TE; Santos, SAO; Neves, BM; Almeida, IF; Costa, PC; Correia-Sa, I; Ventura, SPM; Silvestre, AJD; Freire, MG; Freire, CSR 2019, CARBOHYDRATE POLYMERS, 206, 187-197.
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Odd-Even Effect in the Formation and Extraction Performance of Ionic-Liquid-Based Aqueous Biphasic SystemsBelchior, DCV; Almeida, MR; Sintra, TE; Ventura, SPM; Duarte, IF; Freire, MG 2019, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 58, 19, 8323-8331.
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Synthesis and characterization of analogues of glycine-betaine ionic liquids and their use in the formation of aqueous biphasic systemsPereira, MM; Pedro, SN; Gomes, J; Sintra, TE; Ventura, SPM; Coutinho, JAP; Freire, MG; Mohamadou, A 2019, FLUID PHASE EQUILIBRIA, 494, 239-245.
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Synthesis and characterization of chiral ionic liquids based on quinine, L-proline and L-valine for enantiomeric recognitionSintra, TE; Gantman, MG; Ventura, SPM; Coutinho, JAP; Wasserscheid, P; Schulz, PS 2019, JOURNAL OF MOLECULAR LIQUIDS, 283, 410-416.
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Synthesis and Characterization of Surface-Active Ionic Liquids Used in the Disruption of Escherichia Coli CellsSintra, TE; Vilas, M; Martins, M; Ventura, SPM; Ferreira, AIMCL; Santos, LMNBF; Goncalves, FJM; Tojo, E; Coutinho, JAP 2019, CHEMPHYSCHEM, 20, 5, 727-735.
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