resumo
Cholinium-based ionic liquids are quaternary ammonium salts with a wide range of potential industrial applications. Based on the fact that the cholinium is a complex B vitamin and widely used as food additive, the cholinium-based ionic liquids are generically regarded as environmentally "harmless" and thus, accepted as "non-toxic", although their ecotoxicological profile is poorly known. This work provides new ecotoxicological data for ten cholinium-based salts and ionic liquids, aiming to extend the surprisingly restricted body of knowledge about the ecotoxicity of this particular family and to gain insight on the toxicity mechanism of these compounds. The results reported here show that not all the cholinium tested can be considered harmless towards the test organism adopted. Moreover, the results suggest that the cholinium family exhibits a different mechanism of toxicity as compared to the imidazolium ionic liquids previously described in the literature. (C) 2014 Elsevier Inc. All rights reserved.
palavras-chave
DEEP-EUTECTIC-SOLVENTS; FUNCTIONALIZED SIDE-CHAINS; AQUEOUS 2-PHASE SYSTEMS; DIFFERENT HEAD GROUPS; ACETYLCHOLINESTERASE ENZYME; ANTIMICROBIAL ACTIVITY; TOXICITY EVALUATION; IMIDAZOLIUM; WATER; SALTS
categoria
Environmental Sciences & Ecology; Toxicology
autores
Ventura, SPM; Silva, FAE; Goncalves, AMM; Pereira, JL; Goncalves, F; Coutinho, JAP
nossos autores
Ana Francisca Osório de Almeida Coelho e Silva
Investigador Júnior
Sónia Patrícia Marques Ventura
Professor AuxiliarGrupos
G4 - Materiais Renováveis e Economia Circular
G5 - Materiais Biomiméticos, Biológicos e Vivos
Projectos
agradecimentos
The authors are grateful for the financial support from FEDER funds through the program COMPETE and for national fund through the Portuguese Foundation for Science and Technology (FCT) under the scope of the Projects Pest-C/CTM/LA0011/2013 and PTDC/AAC-AMB/119172/2010. The authors also thank the financial support of FCT considering the post-doctoral Grants SFRH/BPD/79263/2011, SFRH/BPD/79307/2011 and SFRH/BPD/44733/2008 of S.P.M. Ventura, A.M.M. Goncalves and J.L. Pereira, respectively.