resumo
Peppers are the principal source of natural capsaicinoids, a class of bioactive compounds with different therapeutic properties (anticancer, antioxidant, anti-obesity) which make it interesting to the development of extraction and purification processes. This work aims at developing an integrated process of extraction and purification to recover capsaicin from pepper Capsicum frutescens. Thus, ATPS consisting of acetonitrile and some cholinium-based ionic liquids were investigated, characterized and the partition of capsaicin on these systems properly optimized. The main results showed that caps aicin is preferentially migrating for the acetonitrile (top) phase. With a simple technology, mild conditions and less solvents, the success of the capsaicin purification from the pepper biomass was achieved (K-CPS = 60.95 +/- 1.29; EECPS = 90.57 +/- 0.48%, and PFCPS = 3.26 +/- 0.08) using ATPS. Summing up, this work allowed the development of an integrated process of extraction and purification of capsaicin from the chili pepper biomass. (C) 2016 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
palavras-chave
ULTRASOUND-ASSISTED EXTRACTION; BIPHASIC SYSTEMS; PHASE-DIAGRAMS; POLYETHYLENE-GLYCOL; SOLVENT-EXTRACTION; MASS-SPECTROMETRY; PEPPERS; SALTS; DIHYDROCAPSAICIN; CHROMATOGRAPHY
categoria
Engineering
autores
Santos, PL; Santos, LNS; Ventura, SPM; de Souza, RL; Coutinho, JAP; Soares, CMF; Lima, AS
nossos autores
Sónia Patrícia Marques Ventura
Professor Auxiliaragradecimentos
The authors thank CNPq, CAPES and Fundacao de Amparo a Pesquisa e Inovacao Tecnologica do Estado de Sergipe-FAPITEC for financial support and scholarship of P. L. Santos and Programa de Bolsas de Iniciacao Cientifica of Tiradentes University-PROBIC/UNIT scholarship of L. N. S. Santos. This work was developed within the scope of the project CICECO-Aveiro Institute of Materials, POCI-01-0145-FEDER-007679 (FCT Ref. UID/CTM/50011/2013), financed by national funds through the FCT/MEC and when appropriate co-financed by FEDER under the PT2020 Partnership Agreement. The authors are thankful to Fundacao para a Ciencia e Tecnologia for the financial support on the frame of the post-doctoral grant SFRH/BPD/79263/2011 of S.P.M. Ventura.