Opposite Effects Induced by Cholinium-Based Ionic Liquid Electrolytes in the Formation of Aqueous Biphasic Systems Comprising Polyethylene Glycol and Sodium Polyacrylate
authors Bernardo, SC; Capela, EV; Pereira, JFB; Ventura, SPM; Freire, MG; Coutinho, JAP
nationality International
journal MOLECULES
author keywords liquid-liquid equilibrium; cholinium-based ionic liquids; polymeric aqueous biphasic systems; electrolytes; demixing behavior
keywords 2-PHASE SYSTEMS; PHASE-SEPARATION; MOLECULAR-WEIGHT; PROTEIN SEPARATION; ACID) SYSTEM; POLYMER; PEG; PURIFICATION; EXTRACTION; PARTITION
abstract Cholinium-based ionic liquids ([Ch]-based ILs) were investigated as electrolytes in the formation of aqueous biphasic systems (ABS) composed of polyethylene glycol (PEG) and sodium polyacrylate (NaPA) polymers. Both enhancement and decrease in the liquid-liquid demixing ability induced by electrolytes in PEG-NaPA aqueous biphasic systems were observed. It is shown that the ILs that most extensively partition to the PEG-rich phase tend to act as inorganic salts enhancing the two-phase formation ability, while those that display a more significant partition to the NaPA-rich phase decrease the ABS formation capacity. The gathered results allowed us to confirm the tailoring ability of ILs and to identify, for the first time, opposite effects induced by electrolytes on the PEG-NaPA ABS formation ability. The distribution of the electrolyte ions between the coexisting phases and the polyelectrolyte ion compartmentalization are key factors behind the formation of PEG-NaPA-based ABS.
publisher MDPI
isbn 1420-3049
year published 2021
volume 26
issue 21
digital object identifier (doi) 10.3390/molecules26216612
web of science category 13
subject category Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
unique article identifier WOS:000726897600001

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